402. "Constructing Saturated Guanidinum Heterocycles by Cycloaddition of N-Amidinyliminium Ions with Indoles"
T. K. Allred, M. B. Shaghafi, P.-P. Chen, Q. Tran, K. N. Houk, L. E. Overman
Organic Letters 2021, 23, . https://doi.org/10.1021/acs.orglett.1c02832
401. "Potent Anticancer Effects of Epidithiodiketopiperazine NT1721 in Cutaneous T Cell Lymphoma"
M. Lin, C. M. Kowolik, J. Xie, S. Yadav, L. E. Overman, D. A. Horne
Cancers, 2021, 13, 3367. https://doi.org/10.3390/cancers13133367
400. "Strategic Use of Visible-Light Photoredox Catalysis in Natural Product Synthesis"
S. P. Pitre, L. E. Overman
Chem. Rev. 2021, 121, https://doi.org/10.1021/acs.chemrev.1c00247
399. "Reducing the age-associated increase in H3K9 trimethylation restores hippocampal BDNF signaling and synaptic plasticity"
L. Tong, C. Butler, N. Berchtold, A. I. Tucker, K. Tseung, L. Overman, C. W. Cotman
J. Neurosci. 2021, 23, 3611–3622
398. "Lewis Acid Activation of Fragment-Coupling Reactions of Tertiary Carbon Radicals Promoted by Visible Light Irradiation of EDA Complexes"
S. P. Pitre, T. K. Allred, L. E. Overman
Organic Letters 2021, 23, 1103–1106
397. "General Access to Concave-Substituted cis-Dioxabicyclo[3.3.0]octanones: Enantioselective Total Syntheses of Macfarlandin C and Dendrillolide A"
T. K. Allred, A. P. Dieskau, P. Zhao, G. L. Lackner, L. E. Overman
Journal of Organic Chemistry 2020, 85, 15532–15551
396. "Enantioselective Total Synthesis of Macfarlandin C, a Spongian Diterpenoid Harboring a Concave-Substituted cis-Dioxabicyclo[3.3.0]octanone Fragment"
T. K. Allred, A. P. Dieskau, P. Zhao, G. L. Lackner, L. E. Overman
Angewandte Chemie International Edition 2020, 59, 6268–6272
395. "Attenuation of hedgehog/GLI signaling by NT1721 extends survival in pancreatic cancer"
C. M. Kowolik, M. Lin, J. Xie, L. E. Overman, D. A. Horne
Journal of Experimental Clinical Cancer Research 2019, 38:431 (https://doi.org/10.1186/s13046-019-1445-z)
394. "Facile Preparation of Spirolactones by an Alkoxycarbonyl Radical Cyclization Cross-Coupling Cascade"
N. A. Weires, Y. Slutskyy, L. E. Overman
Angewandte Chemie International Edition 2019, 58, 8561–8565
393. "Tertiary Alcohols as Radical Precursors for the Introduction of Tertiary Substituents into Heteroarenes"
S. P. Pitre, M. Muuronen, D. A. Fishman, L. E. Overman
ACS Catalysis 2019, 9, 3413–3418
392. "Forging C(sp3)–C(sp3) Bonds with Carbon-Centered Radicals in the Synthesis of Complex Molecules"
S. P. Pitre, N. A. Weires, L. E. Overman
Journal of the American Chemical Society 2019, 141, 2800–2813
391. "Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space"
S. E. Kearney, L. E. Overman, 98 others authors, Rohde, J. M.
ACS Central Science 2018, 4, 1727–1741
390. "Discussion Addendum for: Preparation of the COP Catalysts: [(S)-COP-OAc]2, [(S)- COP-Cl]2, and (S)-COP-hfacac"
J. S. Cannon, L. E. Overman
Organic Syntheses 2018, 95, 500–511; DOI: 10.15227/orgsyn.095.0500
389. “Total Synthesis of ()-Chromodorolide B by a Computationally-Guided Radical Addition/Cyclization/Fragmentation Cascade”
D. J. Tao, Y. Slutskyy, M. Muuronen, A. Le, P. Kohler, L. E. Overman
Journal of the American Chemical Society 2018, 140, 3091–3102
388. “1,6-Addition of Tertiary Carbon Radicals Generated From Alcohols or Carboxylic Acids by Visible-Light Photoredox Catalysis”
S. Y. Abbas, P. Zhao, L. E. Overman
Organic Letters 2018, 20, 868–871
387. “Short Enantioselective Total Syntheses of Cheloviolenes A and B and Dendrillolide via Convergent Fragment Coupling Using a Tertiary Carbon Radical”
M. R. Garnsey, Y. Slutskyy, C. R. Jamison, P. Zhao, J. Lee, Y. H. Rhee, L. E. Overman
Journal of Organic Chemistry 2018, 83, 6958–6976
386. “Visible-Light Photocatalysis in the Synthesis of Natural Products”
G. L. Lackner, K. W. Quasdorf, L. E. Overman
In Visible Light Photocatalysis in Chemistry, C. Stephenson and D. W. C. MacMillan, Eds., Wiley-VCH, Weinheim, Germany, 2018, Chapter 9, pp 283–297.
385. “Fragment Coupling and Formation of Quaternary Carbons by Visible-Light Photoredox Catalyzed Reaction of tert-Alkyl Hemioxalate Salts and Michael Acceptors”
C. R. Jamison, Y. Slutskyy, L. E. Overman
Organic Syntheses 2017, 94, 167–183
384. “Versatile Construction of 6-Substituted cis-2,8-Dioxabicyclo[3.3.0]octan-3-ones. Short Enantioselective Total Syntheses of Cheloviolenes A and B and Dendrillolide C”
Y. Slutskyy, C. R. Jamison, P. Zhao, J. Lee, Y. H. Rhee, L. E. Overman
Journal of the American Chemical Society 2017, 139, 7192–7195
383. "NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia"
C. M. Kowolik, M. Lin, J. Xie, L. E. Overman and D. A. Horne
Oncotarget 2016, 7, 86186–86197
382. "Palladium(II)-Catalyzed Enantioselective Reactions Using COP Catalysts"
J. S. Cannon and L. E. Overman
Accounts of Chemical Research 2016, 49, 2220–2231
381. “Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular Amastigotes”
L. F. Martins, J. T. Mesquita, E. G. Pinto, T. A. Costa-Silva,S. E. T. Borborema, A. J. G. Junior, B. J. Neves, C. H. Andrade,Z. A. Shuhaib, E. L. Bennett, G. P. Black, P. M. Harper, D. M. Evans, H. S. Fituri, J. P. Leyland, C. Martin, T. D. Roberts, A. J. Thornhill, S. A. Vale, A. Howard-Jones, D. A. Thomas, H. L. Williams, L. E. Overman, R. G. S. Berlinck, P. J. Murphy, and A. G. Tempone
J. Nat. Prod. 2016, 79, 2202–2210
380. "Fragment Coupling With Tertiary Radicals Generated By Visible-Light Photocatalysis"
C. R. Jamison and L. E. Overman
Accounts of Chemical Research 2016, 49, 1578–1586
379. “Generation of the Methoxycarbonyl Radical by Visible-Light Photoredox Catalysis and Its Conjugate Addition with Electron-Deficient Olefins”
Y. Slutskyy and L. E. Overman*
Organic Letters 2016, 18, 2564–2567
378. “Short Enantioselective Total Syntheses of trans-Clerodane Diterpenoids: Convergent Fragment Coupling Using a trans-Decalin Tertiary Radical Generated from a Tertiary Alcohol Precursor”
Y. Slutskyy, C. R. Jamison, G. L. Lackner, D. S. Müller, A. P. Dieskau, N. L. Unteidt, and L. E. Overman
Journal of Organic Chemistry 2016, 81, 7029–7035.
377. “Diastereoselective Coupling of Chiral Acetonide Trisubstituted Radicals with Alkenes”
D. J. Tao, M. Muuronen, Y. Slutskyy, A. Le, F. Furche, and L. E. Overman
Chemistry – A European Journal 2016, 22, 8786–8790
376. “H3K9me3 Inhibition Improves Memory, Promotes Spine Formation and Increases BDNF Levels in the Aged Hippocampus”
S. Snigdha, G. A. Prieto, A. Petrosyan, B. M. Loertscher, A. P. Dieskau, L. E. Overman,
and C. Cotman
Journal of Neuroscience 2016, 36, 3611–3622. PMCID: PMC4804016
375. “Total Synthesis of (–)-Chromodorolide B”
D. J. Tao, Y. Slutzkyy, and L. E. Overman
Journal of the American Chemical Society 2016, 138, 2186–2189. PMCID:PMC 4864965
374. "Ligand-Controlled Diastereoselective 1,3-Dipolar Cycloadditions of Azomethine Ylides With Methacrylonitrile"
M. C. Walton, Y.-F. Yang, X. Hong, K. N. Houk, and L. E. Overman
Organic Letters 2015, 17, 6166–6169
373. "Synthetic Strategies Toward Natural Products Containing Contiguous Stereogenic Quaternary Carbons"
M. Büschleb, S. Dorich, S.Hanessian, D. Tao, K. B. Schenthal, and L. E. Overman
Angewandte Chemie International Edition 2016, 55, 4156–4186. PMCID:PMC 26836448
372. "Synthesis of 2,5-Diaryl-1,5-Dienes from Allylic Bromides Using Visible-Light Photoredox Catalysis"
G. Pratsch and L. E. Overman
Journal of Organic Chemistry 2015, 80, 11388–11397. PMCID: PMC4697828
371. “Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling”
C. C. Nawrat, C. R. Jamison, Y. Slutskyy, D. W. C. MacMillan, and L. E. Overman
Journal of the American Chemical Society 2015, 137, 11270–11273. PMCID: PMC4632490
370. “Tricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity”
M. Baumann, A. P. Dieskau, B. M. Loertscher, M. C. Walton, S. Nam, J. Xie, D. Horne, and L. E. Overman
Chemical Science, 2015, 6, 4451–4457. PMCID: PMC4540405
369. “Constructing Quaternary Carbons from (N-Acyloxy)phthalimide Precursors of Tertiary Radicals Using Visible-Light Photocatalysis”
G. Pratsch, G. L. Lackner and L. E. Overman
Journal of Organic Chemistry, 2015, 80, 6025–6036. PMCID: PMC4699447
368. “Fragment Coupling and the Construction of Quaternary Carbons Using Tertiary Radicals Generated From tert-Alkyl N-Phthalimidoyl Oxalates By Visible-Light Photocatalysis”
G. L. Lackner, Kyle W. Quasdorf, G. Pratsch and L. E. Overman
Journal of Organic Chemistry, 2015, 80, 6012–6024. PMCID: PMC4697963
367. “Stereocontrolled enantioselective total synthesis of the [2+2] quadrigemine alkaloids”
S. M. Canham, B. D. Hafensteiner, A. D. Lebsack, T. L. May-Dracka, S. Nam, B. A. Stearns, and L. E. Overman
Tetrahedron 2015, 71, 6424–6436. PMCID: PMC4526107
366. “Constructing Quaternary Stereogenic Centers Using Tertiary Organocuprates and Tertiary Radicals. Total Synthesis of trans-Clerodane Natural Products”
D. S. Müller, N. L. Untiedt, A. P. Dieskau, G. L. Lackner and L. E. Overman
Journal of the American Chemical Society 2015, 137, 660–663
365. "Catalytic Enantioselective Synthesis of Quaternary Carbon Stereocenters"
K. W. Quasdorf and L. E. Overman
Nature 2014, 516, 181–194. PMCID: PMC4697831
364. "The Insulin Secretory Action of Novel Polycyclic Guanidines: Discovery through Open Innovation Phenotypic Screening, and Exploration of Structure-Activity Relationships"
M. B. Shaghafi, D. G. Barrett, F. S. Willard and L. E. Overman
Bioorganic & Medicinal Chemistry Letters 2014, 24, 1031–1036.
363. "Direct Construction of Quaternary Carbons from Tertiary Alcohols via Photoredox-Catalyzed Fragmentation of tert-Alkyl N-Phthalimidoyl Oxalates"
G. L. Lackner, K. W. Quasdorf and L. E. Overman
Journal of the American Chemical Society 2013, 135, 15342–15345. PMCID: PMC3856227
362. "Enantioselective Synthesis of Angularly Substituted 1-Azabicylic Rings: Coupled Dynamic Kinetic Epimerization and Chirality Transfer"
Z. D. Aron, T. Ito, T. L. May, L. E. Overman and J. Wang
Journal of Organic Chemistry 2013, 78, 9929–9948. PMCID: PMC3843940
361. "Enantioselective Total Synthesis of Plectosphaeroic Acids B and C"
S. Y. Jabri and L. E. Overman
Journal of Organic Chemistry 2013, 78, 8766–8788. PMCID: PMC3819034
360. "Enantioselective Total Synthesis of Plectosphaeroic Acid B"
S. Y. Jabri and L. E. Overman
Journal of the American Chemical Society 2013, 135, 4231–4234 PMCID: PMC3611964
359. "A General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors. Enantioselective Total Syntheses of (+)- and (–)-Gliocladine C, (+)-Leptosin D, (+)-T988C, (+)-Bionectin A and (+)-Gliocladin A"
J. E. DeLorbe, D. Horne, R. Jove, S. M. Mennen, S. Nam, F-L. Zhang and L. E. Overman
Journal of the American Chemical Society 2013, 135, 4117–4128. PMCID: PMC3640572
358. "Origins of Stereoselectivities of Dihydroxylations of cis-Bicyclo[3.3.0]octenes"
H. Wang, P. Kohler, L. E. Overman and K. Houk
Journal of the American Chemical Society 2012, 134, 16054–16058. PMCID: PMC3460691
357. “A Concise Synthesis of (–)-Aplyviolene Facilitated by a Strategic Tertiary Radical Conjugate Addition”
M. J. Schnermann and L. E. Overman
Angewandte Chemie International Edition 2012, 51, 9576–9580. PMCID: PMC3517069
356. “Forming Tertiary Organolithium and Organocuprates from Nitrile Precursors and their Bimolecular Reactions with Carbon Electrophiles to Form Quaternary Carbon Stereocenters”
M. J. Schnermann, N. L. Untiedt, G. Jiménez-Osés, K. N. Houk and L. E. Overman
Angewandte Chemie International Edition 2012, 51, 9581–9586. PMCID: PMC3517041
355. “Total Synthesis of (+)-Sieboldine A: Evolution of A Pinacol-Terminated Cyclization Strategy”
S. M. Canham, D. J. France and L. E. Overman
Journal of Organic Chemistry 2013, 78, 9–34
354. “Palladium(II)-Catalyzed Enantioselective Synthesis of 2-Vinyl Oxygen Heterocycles”
J. S. Cannon, A. C. Olson, L. E. Overman and N. S. Solomon
Journal of Organic Chemistry 2012, 77, 1961–1973. PMCID: PMC3296363
353. “Palladacyclic Imidazoline-Naphthalene Complexes: Synthesis and Catalytic Performance in Pd(II)-Catalyzed Enantioselective Reactions of Allylic Trichloroacetimidates”
J. S. Cannon, J. H. Frederich and L. E. Overman
Journal of Organic Chemistry 2012, 77, 1939–1951. PMCID: PMC3288570
352. “Is There No End to the Total Syntheses of Strychnine? Lessons Learned for Strategy and Tactics in Total Synthesis”
J. S. Cannon and L. E. Overman
Angewandte Chemie International Edition 2012, 51, 4288–4311
351. “Enantioselective Total Synthesis of Aplyviolene”
L. E. Overman and M. J. Schnermann
Journal of the American Chemical Society 2011, 133, 16425–16427. PMCID: PMC3205941
350. “Divergent Synthesis and Chemical Reactivity of Bicyclic Lactone Fragments of Complex Rearranged Spongian Diterpenes”
M. J. Schnermann, C. M. Beaudry, N. E. Genung, S. M. Canham, N. L. Untiedt, B. D. W. Karanikolas, C. Sütterlin and L. E. Overman
Journal of the American Chemical Society 2011, 133, 17494–17503. PMCID: PMC3202687
349. “Identification of an Unexpected 2-Oxonia[3,3]sigmatropic Rearrangement/Aldol Pathway in the Formation of Oxacyclic Rings. Total Synthesis of (+)-Aspergillin PZ” S. M. Canham, L. E. Overman and P. S. Tanis
Tetrahedron 2011, 67, 9837–9843. PMCID: PMC3327308
348. “Enantioselective Total Synthesis of (+)-Gliocladin C and (+)-Gliocladine C. A Convergent Construction of Cyclotryptamine-Fused Polyoxopiperazines and a General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors”
J. E. DeLorbe, S. Y. Jabri, S. M. Mennen, L. E. Overman and F-L. Zhang
Journal of the American Chemical Society 2011, 133, 6549–6552. PMCID: PMC3090078
347. “Total Synthesis of (+)-Condylocarpine (+)-Isocondylocarpine, and (+)-Tubotaiwine”
C. L. Martin, S. Nakamura, R. Otte and L. E. Overman
Organic Letters 2011, 13, 138–141. PMCID: PMC3014433
346. “Total Synthesis of (+)-Nankakurines A and B and (±)-5-epi-Nankakurine A”
R. A. Altman, B. L. Nilsson, L. E. Overman, J. Read de Alaniz, J. M. Rohde and V. Taupin
Journal of Organic Chemistry 2010, 75, 7519–7534. PMCID: PMC3038189
345. “Mechanism of the Cobalt Oxazoline Palladacycle (COP)-Catalyzed Asymmetric Synthesis of Allylic Esters”
J. S. Cannon, S. F. Kirsch, L. E. Overman and H. F. Sneddon
Journal of the American Chemical Society 2010, 132, 15192–15203. PMCID: PMC 2967776
344. “Catalytic Asymmetric Synthesis of Chiral Allylic Esters”
J. S. Cannon, S. F. Kirsch and L. E. Overman
Journal of the American Chemical Society 2010, 132, 15185–15191. PMCID: PMC 2966826
343. “Terminating Catalytic Asymmetric Heck Cyclizations by Stereoselective Intramolecular Capture of 3-Allylpalladium Intermediates: Total Synthesis of (–)-Spirotryprostatin B and Three Stereoisomers”
L. E. Overman and M. D. Rosen
Tetrahedron 2010, 66, 6514–6525. PMCID: PMC 2921616
342. “Total Synthesis of (+)-Sieboldine A”
S. M. Canham, D. J. France and L. E. Overman
Journal of the American Chemical Society 2010, 132, 7876–7877. PMCID: PMC 2885033
341. “Enantioselective Synthesis of Angularly Substituted 1-Azabicyclic Ring Systems: Dynamic Kinetic Resolution Using Aza-Cope Rearrangements”
T. Ito, L. E. Overman and J. Wang,
Journal of the American Chemical Society 2010, 132, 3272–3273. PMCID: PMC2858009
340. “Golgi Modifying Properties of Macfarlandin E and the Synthesis and Evaluation of Its 2,7-Dioxabicyclo[3.2.1]octan-3-one Core”
M. J. Schnermann, C. M. Beaudry, A. V. Egorova, R. S. Polishchuk, C. Suetterlin and L. E. Overman
Proceedings of the National Academy of Science (USA), 2010, 107, 6158–6163. PMCID: PMC 2851978
339. “Total Synthesis of ()- and (–)-Actinophyllic Acid”
C. L. Martin, L. E. Overman and J. A. Rohde
Journal of the American Chemical Society 2010, 132, 4894–4906. PMCID: PMC 2851836
338. “Origin of Stereocontrol in the Construction of the 12-Oxatricyclo[6.3.1.02,7]dodecane Ring System by Prins–Pinacol Reactions”
L. E. Overman and P. A. Tanis
Journal of Organic Chemistry 2010, 75, 455–463. PMCID: PMC3077117
337. “The Aza-Cope-Mannich Reaction”
L. E. Overman, P. G. Humphreys and G. S. Welmaker
Organic Reactions 2011, 75, pp 747–820
336. “Catalytic Asymmetric Synthesis of Branched Chiral Allylic Phenyl Ethers from (E)-Allylic Alcohols”
A. C. Olson, L. E. Overman, H. F. Sneddon and J. W. Ziller
Advanced Synthesis & Catalysis 2009, 351, 3186–3192
335. “Asymmetric Construction of Rings A–D of Daphnicyclidin Type Alkaloids”
T. B. Dunn, J. M. Ellis, C. C. Kofink, J. R. Manning and L. E. Overman
Organic Letters 2009, 11, 5658–5661. PMCID: PMC2996462
334. “A Unified Strategy for Enantioselective Total Synthesis of Cladiellin and Briarellen Diterpenes: Total Synthesis of Briarellins E and F, and the Putative Structure of Alcyonin and Revision of Its Structure Assignment”
O. Corminboeuf, L. E. Overman and L. D. Pennington
Journal of Organic Chemistry 2009, 74, 5458–5470. PMCID: PMC 2744073
333. “Molecular Rearrangements in the Construction of Complex Molecules”
L. E. Overman
Tetrahedron 2009, 65, 6432–6446. PMCID: PMC 2967776
332. “Absolute Configuration of Actinophyllic Acid as Determined through Chiroptical Data”
T. Taniguchi, C. L. Martin, K. Monde, K. Nakanishi, N. Berova and L. E. Overman
Journal of Natural Products 2009, 72, 430–432. PMCID: PMC 2902975
331. “A Versatile Synthesis of Unsymmetrical 3,3'-Bioxindoles: Stereoselective Mukaiyama Aldol Reactions of 2-Siloxyindoles with Isatins”
J. M. Ellis, L. E. Overman, H. R. Tanner and J. Wang
Journal of Organic Chemistry 2008, 73, 9151–9154. PMCID: PMC 2634855
330. “Enantioselective Total Syntheses of Nankakurines A and B: Confirmation of Structure and Establishment of Absolute Configuration”
Journal of the American Chemical Society 2008, 130, 11297–11299. PMCID: PMC3074941
B. L. Nilsson, L. E. Overman, J. Read de Alaniz and J. M. Rohde
329. “Total Synthesis of (–)-Actinophyllic Acid”
C. L. Martin, L. E. Overman and J. M. Rohde
Journal of the American Chemical Society 2008, 130, 7568–7569. PMCID: PMC 2654095
328. “Catalytic Asymmetric Synthesis of Allylic Thiol Derivatives”
L. E. Overman, S. W. Roberts and H. Sneddon Organic Letters 2008, 10, 1485–1488
327. “Total Synthesis of the Strychnos Alkaloid (+)–Minfiensine: Tandem Enantioselective Intramolecular Heck-Iminium Ion Cyclization”
A. B. Dounay, P. G. Humphreys, L. E. Overman and A. D. Wrobleski
Journal of the American Chemical Society 2008, 130, 5368–5377. PMCID: PMC 2995331
326. “Construction of Epidithiodioxopiperazines by Directed Oxidation of Hydroxyproline-Derived Dioxopiperazines”
L. E. Overman and T. Sato Organic Letters 2007, 9, 5267–5270
325. “On the Structure of Palau’amine: Evidence for the Revised Relative Configuration from Chemical Synthesis”
Journal of the American Chemical Society 2007, 129, 12896–12900. PMCID: PMC 2593883
B. A. Lanman, L. E. Overman, R. Paulini and N. S. White
324. “Synthesis of All Low-Energy Stereoisomers of the Tris(pyrrolidinoindoline) Alkaloid Hodgkinsine and Preliminary Assessment of Their Antinociceptive Activity”
Journal of Organic Chemistry 2007, 72, 7909–7914
J. J. Kodanko, S. Hiebert, E. A. Peterson, L. Sung, L. E. Overman, V. de Moura Linck, G. C. Goerck, T. A. Amador, M. B. Leal and E. Elisabetsky
323. “Total Synthesis of (–)-Sarain A”
Journal of the American Chemical Society 2007, 129, 11987–12002
M. H. Becker, P. Chua, R. Downham, C. J. Douglas, N. K. Garg, S. Hiebert, S. Jaroch, R. T. Matsuoka, J. A. Middleton, F. W. Ng and L. E. Overman
322. “The Asymmetric Intramolecular Mizoroki-Heck Reaction in Natural Product Synthesis” The Mizoroki-Heck Reaction; M. Oestreich, Ed.; Wiley–VCH, West Sussex, UK, 2009, Chapter 16, pp 533–568
A. B. Dounay and L. E. Overman
321. “Total Synthesis of (+)-Asperazine”
Tetrahedron 2007, 63, 8499–8513
S. P. Govek and L. E. Overman
320. “Total Synthesis of Complex Cyclotryptamine Alkaloids: Stereocontrolled Construction of Quarternary Carbon Stereocenters”
Angewandte Chemie, International Edition 2007, 46, 5488–5508
A. Steven and L. E. Overman
319. “Kinetic and Computational Analysis of the Palladium(II)-Catalyzed Asymmetric Allylic Trichloroacetimidate Rearrangement. Development of a Model for Enantioselectivity”
Journal of the American Chemical Society 2007, 129, 5031–5044
M. P. Watson, L. E. Overman and R. G. Bergman
318. “Catalytic Asymmetric Synthesis of Allylic Aryl Ethers”
Organic Letters 2007, 9, 911–913
S. F. Kirsch, L. E. Overman and N. White
317. “Enantioselective Total Synthesis of (+)-Gliocladin C”
Organic Letters 2007, 9, 339–341: PMCID: PMC 2526118
L. E. Overman and Y. Shin
316. “Preparation of the COP Catalysts: [(S)-COP-OAc]2, [(S)-COP-Cl]2, and (S)-COP-hfacac”
Organic Syntheses 2007, 84, 148–155
C. E. Anderson, S. F. Kirsch, L. E. Overman, C. J. Richards and M. P. Watson
315. “Preparation of (5-(S)-2-(4-Methylethyl)-Oxazolinylcyclopentadienyl)-(4-Tetraphenylcylcobutadiene)Cobalt”
Organic Syntheses 2007, 84, 139–147
C. E. Anderson, L. E. Overman, C. J. Richards, M. P. Watson and N. White
314. “Evaluation of Strategies for the Synthesis of the Guanidine Hemiaminal Portion of Palau’amine”
Heterocycles 2006, 70, 557–570: PMCID: PMC 2600862
B. A. Lanman and L. E. Overman
313. “Enantioselective Total Synthesis of Guanacastepene N Using an Uncommon 7-Endo Heck Cyclization as a Pivotal Step”
Journal of the American Chemical Society 2006, 128, 13095–13101
S. Iimura, L. E. Overman, R. Paulini and A. Zakarian
312. “Stereocontrolled Synthesis of Functionalized cis-Cyclopentapyrazolidines by 1,3-Dipolar Cycloaddition Reactions of Azomethine Imines”
Journal of Organic Chemistry 2006, 71, 9144–9152: PMCID: PMC 2516743
J. Gergely, J. B. Morgan and L. E. Overman
311. “Concise Synthesis of Guanidine-Containing Heterocycles Using the Biginelli Reaction”
Journal of Organic Chemistry 2006, 71, 7706–7714: PMCID: PMC 2535792
B. L. Nilsson and L. E. Overman
310. “The Total Synthesis of (–)-Sarain A”
Angewandte Chemie, International Edition 2006, 45, 2912–2915
N. K. Garg, S. Hiebert and L. E. Overman
309. “Diastereoselection in the Formation of Contiguous Quaternary Carbon Stereocenters by the Intramolecular Heck Reaction”
Journal of Organic Chemistry 2006, 71, 2600–2608: PMCID: PMC 2535793
L. E. Overman and D. A. Watson
308. “Diastereoselection in the Formation of Spirocyclic Oxindoles by the Intramolecular Heck Reaction”
Journal of Organic Chemistry 2006, 71, 2587–2599: PMCID: PMC 2585599
L. E. Overman and D. A. Watson
307. “Scope and Facial Selectivity of the Prins–Pinacol Synthesis of Attached Rings”
Journal of Organic Chemistry 2006, 71, 1581–1587
L. E. Overman and E. J. Velthuisen
306. “Enantioselective Total Synthesis of the Proposed Structure of Batzelladine F and Definition of Its Structure”
Journal of the American Chemical Society 2006, 128, 2604–2608: PMCID: PMC 2535800
F. Cohen and L. E. Overman
305. “Evolution of a Strategy for the Synthesis of Structurally Complex Batzelladine Alkaloids. Enantioselective Total Synthesis of the Proposed Structure of Batzelladine F and Structural Revision”
Journal of the American Chemical Society 2006, 128, 2594–2603: PMCID: PMC 2535801
F. Cohen and L. E. Overman
304. “Synthesis of Dihydroquinolinones Angularly Fused to Tetrahydrobenzazepinone Rings”
Heterocycles 2006, 67, 585–588
L. E. Overman and E. A. Peterson
303. “Use of the Intramolecular Heck Reaction for Forming Congested Quaternary Carbon Stereocenters: Stereocontrolled Total Synthesis of (±)-Gelsemine”
Journal of the American Chemical Society 2005, 127, 18054–18065: PMCID: PMC 2597289
A. Madin, C. J. O’Donnell, T. Oh, D. W. Old, L. E. Overman and M. J. Sharp
302. “Aza-Cope Rearrangement–Mannich Cyclizations for the Formation of Complex Tricyclic Amines: Stereocontrolled Total Synthesis of (±)-Gelsemine”
Journal of the American Chemical Society 2005, 127, 18046–18053: PMCID: PMC 2570375
W. G. Earley, E. J. Jacobsen, A. Madin, G. P. Meier, C. J. O’Donnell, T. Oh, D. W. Old, L. E. Overman and M. J. Sharp
301. “Total Synthesis of (–)-Crambidine and Definition of the Relative Configuration of its Unique Tetracyclic Guanidinium Core”
Journal of the American Chemical Society 2005, 127, 15652–15658
L. E. Overman and Y. H. Rhee
300. “Sequential Catalytic Asymmetric Heck–Iminium Ion Cyclization: Enantioselective Total Synthesis of the Strychnos Alkaloid Minfiensine”
Journal of the American Chemical Society 2005, 127, 10186–10187
A. B. Dounay, L. E. Overman and A. D. Wrobleski
299. “Asymmetric Construction of Quaternary Carbon Stereocenters: High Stereoselection in Mukaiyama Aldol Reactions of 2-Siloxyindoles with Chiral Aldehydes”
Organic Letters 2005, 7, 2795–2797
S. Adhikari, S. Caille, M. Hanbauer, V. X. Ngo and L. E. Overman
298. “Asymmetric Rearrangement of Allylic Trichloroacetimidates: Preparation of (S)-2,2,2-Trichloro-N-(1-propylallyl)acetamide”
Organic Syntheses 2005, 82, 134–139
C. E. Anderson, L. E. Overman and M. P. Watson
297. “Catalytic Asymmetric Intramolecular Aminopalladation: Improved Palladium(II) Catalysts”
Journal of Organic Chemistry 2005, 70, 2859–2861
S. F. Kirsch and L. E. Overman
296. “Catalytic Asymmetric Synthesis of Chiral Allylic Esters”
Journal of the American Chemical Society 2005, 127, 2866–2867
S. F. Kirsch and L. E. Overman
295. “Toward an Enantioselective Total Synthesis of Sarain A: Construction of an Advanced Intermediate and Rearrangement of the Sarain A Core Under Mild Conditions”
Organic Letters 2005, 7, 933–936
C. J. Douglas, S. Hiebert and L. E. Overman
294. “Stereocontrolled Synthesis of Angularly-Substituted 1-Azabicyclic Rings by Cationic 2-Aza-Cope Rearrangements”
Organic Letters 2005, 7, 913–916
Z. D. Aron and L. E. Overman
293. “Total Synthesis and Properties of the Crambescidin Core Zwitterionic Acid and Crambescidin 359”
Journal of the American Chemical Society 2005, 127, 3380–3390
Z. D. Aron and L. E. Overman
292. “Synthesis of tert-Leucine-Derived Cobalt Oxazoline Palladacycles. Reversal of Palladation Diastereoselectivity and Application to the Asymmetric Rearrangement of N-Aryl Trifluoroacetimidates”
Organometallics 2005, 24, 77–81
R. S. Prasad, C. E. Anderson, C. J. Richards and L. E. Overman
291. “The Allylic Trihaloacetimidate Rearrangement”
Organic Reactions 2005, 66, 1–107
N. E. Carpenter and L. E. Overman
290. “Catalytic Asymmetric Synthesis of Chiral Allylic Amines. Evaluation of Ferrocenyloxazoline Palladacycle Catalysts and Imidate Motifs”
Journal of Organic Chemistry 2005, 70, 648–657
C. E. Anderson, Y. Donde, C. J. Douglas and L. E. Overman
289. “Enantioselective Synthesis of Six-Membered Palladacycles Having Metal-Bound Stereogenic Carbons: Isolation and Reactivity of Palladacycles Containing Readily Accessible -Hydrogens”
Journal of the American Chemical Society 2004, 126, 16820–16833
B. J. Burke and L. E. Overman
288. “Stereocontrolled Construction of Either Stereoisomer of 12-Oxatricyclo[6.3.1.02,7]-dodecanes Using Prins-Pinacol Reactions”
Organic Letters 2004, 6, 3853–3856
L. E. Overman and E. J. Velthuisen
287. “Monomeric Cobalt Oxazoline Palladacycles (COP). Useful Catalysts for Catalytic Asymmetric Rearrangement of Allylic Trichloroacetimidates”
Journal of Organic Chemistry 2004, 69, 8101–8104
S. F. Kirsch, L. E. Overman and M. P. Watson
286. “Guanidine Alkaloid Analogs as Inhibitors of HIV-1 Nef Interactions with p53, Actin, and p56lck”
Proceedings of the National Academy of Science USA 2004, 101, 14079–14084: PMCID: PMC 521092
A. Olszewski, K. Sato, Z. D. Aron, F. Cohen, A. Harris, B. R. McDougall, W. E. Robinson, Jr., L. E. Overman and G. A. Weiss
285. “Asymmetric Synthesis of Pyrrolidinoindolines. Application for the Practical Total Synthesis of (–)-Phenserine”
Journal of the American Chemical Society 2004, 126, 14043–14053
A. Huang, J. J. Kodanko and L. E. Overman
284. “Studies Towards the Total Synthesis of Palau’amine. Formation of 4,5-Dihydropyrrole-2-carboxylate Intermediates by Alkene–Enamide Ring-Closing Metathesis”
Tetrahedron 2004, 60, 9559–9568
J. D. Katz and L. E. Overman
283. “Inhibition of HIV-1 Envelope-Mediated Fusion by Synthetic Batzelladine Analogs”
Journal of Natural Products 2004, 67, 1319–1324
C. A. Bewley, S. Ray, F. Cohen, S. K. Collins and L. E. Overman
282. “Synthesis and Anticancer Activity of Side Chain Analogs of the Crambescidin Alkaloids”
Bioorganic & Medicinal Chemistry Letters 2004, 14, 3445–3449
Z. D. Aron, H. Pietraszkiewicz, L. E. Overman, F. Valeriote and C. Cuevas
281. “Contiguous Stereogenic Quaternary Carbons: A Daunting Challenge in Natural Products Synthesis”
Proceedings of the National Academy of Science USA 2004, 101, 11943–11948: PMCID: PMC 514413
E. A. Peterson and L. E. Overman
280. “Enantioselective Total Synthesis of (–)-Dehydrobatzelladine C”
Organic Letters 2004, 6, 1253–1255
S. K. Collins, A. I. McDonald, L. E. Overman and Y. H. Rhee
279. “Scope and Limitations of the Thionium Ion-Initiated Prins–Pinacol Synthesis of Carbocycles”
Synlett 2004, 1387–1393
B. J. Burke, A. D. Lebsack and L. E. Overman
278. “Catalytic Asymmetric Synthesis of All-Carbon Quaternary Stereocenters”
Proceedings of the National Academy of Sciences USA 2004, 101, 5363–5367: PMCID: PMC 397386
C. J. Douglas and L. E. Overman
277. “Total Syntheses of (±)-Didehydrostemofoline (Asparagamine A) and (±)-Isodidehydrostemofoline”
Journal of the American Chemical Society 2003, 125, 15284–15285
M. Brüggemann, A. I. McDonald, L. E. Overman, M. D. Rosen, L. Schwink and J. P. Scott
276. “The Tethered Biginelli Condensation in Natural Product Synthesis”
Chemical Communications 2004, 253–265
Z. D. Aron and L. E. Overman
275. “Assembling Polycyclic Bisguanidine Motifs Resembling Batzelladine Alkaloids by Double Tethered Biginelli Condensations”
Organic Letters 2003, 5, 4485–4488
F. Cohen, S, K. Collins and L. E. Overman
274. “Palladium”
Chemical & Engineering News 2003, September 8, p 116
L. E. Overman
273. “Catalytic Asymmetric Rearrangement of Allylic Trichloroacetimidates. A Practical Method for Preparing Allylic Amines and Congeners of High Enantiomeric Purity”
Journal of the American Chemical Society 2003, 125, 12412–12413
C. E. Anderson and L. E. Overman
272. “Strategic Use of Pinacol-Terminated Prins Cyclizations in Target-Oriented Total Synthesis”
Journal of Organic Chemistry 2003, 68, 7143–7157
L. E. Overman and L. D. Pennington
271. “Enantioselective Synthesis of (–)-Idiospermuline”
Tetrahedron 2003, 59, 6905–6919
L. E. Overman and E. A. Peterson
270. “Catalytic Asymmetric Rearrangement of Allylic N-Aryl Trifluoroacetimidates. A Useful Method for Transforming Prochiral Allylic Alcohols to Chiral Allylic Amines”
Organic Letters 2003, 5, 1809–1812
L. E. Overman, C. E. Owen, M. M. Pavan, C. J. Richards
269. “Enantioselective Total Synthesis of Briarellins E and F. The First Total Syntheses of Briarellin Diterpenes”
Journal of the American Chemical Society 2003, 125, 6650–6652
O. Corminboeuf, L. E. Overman and L. D. Pennington
268. “Enantioselective Total Syntheses of the Cyclotryptamine Alkaloids Hodgkinsine and Hodgkinsine B”
Angewandte Chemie, International Edition 2003, 42, 2528–2531
J. J. Kodanko and L. E. Overman
267. “Enantioselective Total Synthesis of the Cyclotryptamine Alkaloid Idiospermuline”
Angewandte Chemie, International Edition 2003, 42, 2525–2528
L. E. Overman and E. A. Peterson
266. “Total Synthesis of the Reputed Structure of Alcyonin and Reassignment of its Structure”
Organic Letters 2003, 5, 1543–1546
O. Corminboeuf, L. E. Overman and L. D. Pennington
265. “Catalytic Asymmetric Synthesis of Quaternary Carbons Bearing Two Aryl Substituents. Enantioselective Synthesis of 3-Alkyl-3-Aryl Oxindoles by Catalytic Asymmetric Intramolecular Heck Reactions”
Journal of the American Chemical Society 2003, 125, 6261–6271
A. B. Dounay, K. Hatanaka, J. J. Kodanko, M. Oestreich, L. E. Overman, L. A. Pfeifer and M. M. Weiss
264. “The Asymmetric Intramolecular Heck Reaction in Natural Product Total Synthesis”
Chemical Reviews 2003, 103, 2945–2963
L. E. Overman and A. Dounay
263. “Stereocontrolled Synthesis of Triazacyclopenta[cd]pentalenes by Intramolecular 1,3-Dipolar Cycloaddition Reactions of Azomethine Imines”
Journal of Organic Chemistry 2002, 67, 7880–7883
G. Bélanger, F-T. Hong, L. E. Overman, B. N. Rogers, J. T. Tellew and W. C. Trenkle
262. “Diastereoselective Lithiation of (6-Arene)dicarbonyltriphenylphosphane Chromium(0) Oxazoline Complexes—Direct Preparation of Enantiopure Complexes Having Planar Chiral Fragments of Either Configuration”
Angewandte Chemie, International Edition 2002, 41, 3884–3887
L. E. Overman, C. E. Owen and G. G. Zipp
261. “New Cationic Olefin Cyclization–Pinacol Reactions. Ring-Expanding Cyclopentane Annulations that Directly Install Useful Functionality in the Cyclopentane Ring”
Journal of Organic Chemistry 2002, 67, 6421–6429
L. E. Overman and J. P. Wolfe
260. “Enantioselective Total Synthesis of Quadrigemine C and Psycholeine”
Journal of the American Chemical Society 2002, 124, 9008–9009
A. D. Lebsack, J. T. Link, L. E. Overman and B. A. Stearns
259. “Stereoselective Synthesis of Carbocyclic Ring Systems by Pinacol-Terminated Prins Cyclizations”
Tetrahedron 2002, 58, 6473–6483
T. C. Gahman and L. E. Overman
258. “Preparation of -Sulfenyl Enones by Thermal Fragmentation of -Sulfenyl Enol Triflates”
Organic Letters 2002, 4, 929–931
J. Hynes, Jr., T. Nasser, L. E. Overman and D. A. Watson
257. “Construction of Substituted Cyclohexanones by Reductive Cyclization of 7-Oxo-2,8-alkadienyl Esters”
Organic Letters 2002, 4, 79–82
T. M. Kamenecka, L. E. Overman and S. K. L. Sakata
256. “Catalytic Asymmetric Intramolecular Aminopalladation: Enantioselective Synthesis of Vinyl-Substituted 2-Oxazolidinones, 2-Imidazolidinones and 2-Pyrrolidinones”
Journal of the American Chemical Society 2002, 124, 12–13
L. E. Overman and T. P. Remarchuk
255. “Enantioselective Total Synthesis of Batzelladine F: Structural Revision and Stereochemical Definition”
Journal of the American Chemical Society 2001, 123, 10782–10783
F. Cohen and L. E. Overman
254. “Enantioselective Total Syntheses of Ditryptophenaline and ent-WIN 64821”
Journal of the American Chemical Society 2001, 123, 9465–9467
L. E. Overman and D. V. Paone
253. “Total Synthesis of Asperazine”
Journal of the American Chemical Society 2001, 123, 9468–9469: PMCID: PMC 1987397
S. P. Govek and L. E. Overman
252. “A General Strategy for the Synthesis of Cladiellin Diterpenes. Enantioselective Total Syntheses of 6-Acetoxycladiell-7(16),11-dien-3-ol (a.k.a. Deacetoxyalcyonin Acetate), Cladiell-11-ene-3,6,7-triol, Sclerophytin A and the Initially Purported Structure of Sclerophytin A”
Journal of the American Chemical Society 2001, 123, 9033–9044
D. W. C. MacMillan, L. E. Overman and L. D. Pennington
251. “Enantioselective Total Synthesis of Shahamin K”
Journal of the American Chemical Society 2001, 123, 4851–4852
A. D. Lebsack, L. E. Overman and R. J. Valentegovich
250. “A New Asymmetric Synthesis of trans-Hydroisoquinolones”
Organic Letters 2001, 3, 1229–1232
A. Kamatani and L. E. Overman
249. “Stereoselection in the Prins-Pinacol Synthesis of Acyltetrahydrofurans”
Organic Letters 2001, 3, 1225–1228
F. Cohen, D. W. C. MacMillan, L. E. Overman and A. Romero
248. “Synthesis of Polycyclic Guanidines by Cyclocondensation Reactions of N-Amidinyliminium Ions”
Journal of Organic Chemistry 2001, 66, 3167–3175
L. E. Overman and J. P. Wolfe
247. “Use of Sequential Intramolecular Heck Cyclizations for Preparing Bicyclo[3.2.1]octane Fragments of Tetracyclic Stemodane and Stemarane Diterpenes”
Synlett 2001, 1009–1012
S. J. O’Connor, L. E. Overman and P. V. Rucker
246. “Thwarting ß-Hydride Elimination: Capture of the Alkylpalladium Intermediate of an Asymmetric Intramolecular Heck Reaction”
Angewandte Chemie, International Edition 2001, 40, 1439–1442
M. Oestreich, P. R. Dennison, J. J. Kodanko and L. E. Overman
245. “Enantioselective Synthesis of Authentic Schlerophytin A, Sclerophytin B, and Cladiell-11-ene-3,6,7-triol”
Organic Letters 2001, 3, 135–137
F. Gallou, D. W. C. MacMillan, L. E. Overman, L. A. Paquette, L. D. Pennington and J. Yang
244. “Catalytic Asymmetric Synthesis of Quaternary Carbon Centers by Intramolecular Heck Reaction: Synthetic Developments and Mechanistic Studies”
Journal of Synthetic Organic Chemistry, JAPAN 2000, 58, 718–727
A. Ashimori and L. E. Overman
243. “Total Synthesis of (–)-Spirotryprostatin B and Three Stereoisomers”
Angewandte Chemie, International Edition 2000, 39, 4596–4599
L. E. Overman and M. D. Rosen
242. “Synthesis of 3-Acyltetrahydrofurans from Formaldehyde Acetals of Allylic Diols”
Tetrahedron Letters 2000, 41, 9431–9435
C. M. Gasparski, P. M. Herrinton, L. E. Overman and J. P. Wolfe
241. “Investigation of a Dialkylation Approach for Enantioselective Construction of Vicinal Quaternary Stereocenters”
Organic Letters 2000, 2, 3241–3244
S. B. Hoyt and L. E. Overman
240. “Total Synthesis of the Supposed Structure of Sclerophytin A and an Improved Route to (–)-7-Deacetoxyalcyonin Acetate”
Organic Letters 2000, 2, 2683–2686
L. E. Overman and L. D. Pennington
239. “A New Method for Stereocontrolled Synthesis of Substituted Tetrahydrothiophenes”
Journal of the American Chemical Society 2000, 122, 8672–8676
A. M. Ponce and L. E. Overman
238. “Enantioselective Total Syntheses of 13,14,15-Isocrambescidin 800 and 13,14,15-Isocrambescidin 657”
Journal of the American Chemical Society 2000, 122, 4904–4914
D. S. Coffey, L. E. Overman and F. Stappenbeck
237. “A Practical Entry to the Crambescidin Family of Guanidine Alkaloids. Enantioselective Total Syntheses of Ptilomycalin A, Crambescidin 657 and its Methyl Ester (Neofolitispate 2) and Crambescidin 800”
Journal of the American Chemical Society 2000, 122, 4893–4903
D. S. Coffey, A. I. McDonald, L. E. Overman, M. H. Rabinowitz and P. A. Renhowe
236. “Stereoselection in the Prins–Pinacol Synthesis of 2,2-Disbustituted 4-Acyltetrahydrofurans. Enantioselective Synthesis of (–)-Citreoviral”
Organic Letters 2000, 2, 223–226
N. Hanaki, J. T. Link, D. W. C. MacMillan, L. E. Overman, W. G. Trankle and J. A. Wurster
235. “Investigations Directed at the Total Synthesis of Ouabain. Lessons Learned from Degradation Studies”
Heterocycles 2000, 52, 1297–1314
L. E. Overman and P. V. Rucker
234. “Asymmetric Total Synthesis of Batzelladine D”
Organic Letters 1999, 1, 2169–2172
F. Cohen, L. E. Overman and S. K. L. Sakata
233. “A New Strategy for Synthesis of Attached Rings”
Canadian Journal of Chemistry 2000, 78, 732–738
L. E. Overman and L. D. Pennington
232. “Enantioselective Total Synthesis of the Kinesin Motor Protein Inhibitor Adociasulfate 1”
Journal of the American Chemical Society 1999, 121, 12206–12207
M. Bogenstätter, A. Limberg, L. E. Overman and A. L. Tomasi
231. “Enantioselective Construction of Vicinal Stereogenic Quaternary Centers by Dialkylation: Practical Total Syntheses of (+)- and Meso-Chimonanthine”
Angewandte Chemie, International Edition 2000, 39, 213–215
L. E. Overman, J. F. Larrow, B. A. Stearns and J. M. Vance
230. “Preparation of (3S)-N-N-1,7-Bis-tert-butoxycarbonyl-3-hydroxyspermidine in High Enantiomeric Purity”
Journal of Organic Chemistry 1999, 64, 8741–8742
D. S. Coffey, A. I. McDonald and L. E. Overman
229. “A Suzuki Coupling Method for Directly Introducing a Protected -Aminoethyl Group into Arenes and Alkenes. Convenient Synthesis of Phenethyl and Homoallylic Amines”
Journal of Organic Chemistry 1999, 64, 8743–8744
A. Kamatani and L. E. Overman
228. “Direct Stereo- and Enantiocontrolled Synthesis of Vicinal Stereogenic Quaternary Carbon Centers. Total Synthesis of meso- and (–)-Chimonanthine and (+)-Calycanthine”
Journal of the American Chemical Society 1999, 121, 7702–7703
L. E. Overman, D. V. Paone and B. A. Stearns
227. “Total Synthesis of (±)-Gelsemine”
Angewandte Chemie, International Edition 1999, 38, 2934–2936
A. Madin, C. J. O'Donnell, T. Oh, D.W. Old, L. E. Overman and M. J. Sharp
226. “Enantioselective Total Synthesis of 13,14,15-Isocrambescidin 800”
Journal of the American Chemical Society 1999, 121, 6944–6945
D. Coffey, A. I. McDonald, L. E. Overman and F. Stappenbeck
225. “Enantiodivergent Total Synthesis of (+)- and (–)-Scopadulcic Acid A”
Journal of the American Chemical Society 1999, 121, 5467–5480
M. E. Fox, C. Li, J. P. Marino, Jr. and L. E. Overman
224. “High Enantioselection in the Rearrangement of Allylic Imidates with Ferrocenyl Oxazoline Catalysts”
Journal of the American Chemical Society 1999, 121, 2933–2934.
Y. Donde and L. E. Overman
223. “Palladium Catalyzed Enantioselective Rearrangement of Allylic Imidates to Allylic Amides”
Journal of Organometallic Chemistry 1999, 576/1-2, 290–299
T. K. Hollis and L. E. Overman
222. “Asymmetric Intramolecular Heck Reactions”
Catalytic Asymmetric Synthesis, Second Edition; I. Ojima, Ed., Wiley: New York; 2000, Chapter 8G, pp 675–697
Y. Donde and L. E. Overman
221. “Studies Towards a Total Synthesis of Sarains A–C. Stereospecific Condensation of ,-Unsaturated Esters With the Phenyl Oxazoline Derivative of Threonine”
Tetrahedron Letters 1999, 40, 1273–1276
S. Jaroch, R. T. Matsuoka and L. E. Overman
220. “Stereocontrolled Synthesis of Trisubstituted Tetrahydropyrans”
Journal of the American Chemical Society 1999, 121, 1092–1093
M. J. Cloninger and L. E. Overman
219. “Tuning Stereoselection in Tethered Biginelli Condensations. Synthesis of cis or trans 1-Oxo- and 1-Iminohexahydropyrrolo-[1,2-c]pyrimidines”
Journal of Organic Chemistry 1999, 64, 1520–1528
A. I. McDonald and L. E. Overman
218. “Application of the Tethered Biginelli Reaction for Enantioselective Synthesis of Batzelladine Alkaloids. Absolute Configuration of the Tricyclic Guanidine Portion of Batzelladine B”
Journal of Organic Chemistry 1999, 64, 1512–1519
A. S. Franklin, S. K. Ly, G. H. Mackin, L. E. Overman and A. J. Shaka
217. “Total Synthesis of (+)-Aloperine. Use of a Nitrogen-Bound Silicon Tether in an Intramolecular Diels–Alder Reaction”
Journal of the American Chemical Society 1999, 121, 700–709
A. D. Brosius, L. E. Overman and L. Schwink
216. “Asymmetric Construction of the Diazatricyclic Core of the Marine Alkaloids Sarains A-C”
Journal of Organic Chemistry 1998, 63, 8096–8097
R. Downham, F. W. Ng and L. E Overman
215. “Planar-Chiral Cyclopalladated Ferrocenyl Amines and Imines as Enantioselective Catalysts for Allylic Imidate Rearrangements”
Tetrahedron: Asymmetry 1998, 9, 3213–3222
F. Cohen and L.E. Overman
214. “Forming Cyclics with the Intramolecular Heck Reaction”
CHEMTECH 1998, 28(8), August, 19–26
J. T. Link and L. E. Overman
213. “Stereoselectivities of Nucleophilic Additions to Cycloheptanones. Experimental and Theoretical Studies and General Purpose Force Field for the Prediction of Nucleophilic Addition Stereoselectivities”
Journal of Organic Chemistry 1998, 63, 3196–3203
K. Ando, K. R. Condroski, K. N. Houk, Y.-D. Wu, S. K. Ly and L. E. Overman
212. “Catalytic Asymmetric Synthesis of Either Enantiomer of the Calabar Alkaloids Physostigmine and Physovenine”
Journal of the American Chemical Society 1998, 120, 6500–6503
T. Matsuura, L. E. Overman and D. J. Poon
211. “Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Studies of Intramolecular Heck Reactions of (Z)-,-Unsaturated Anilides and Mechanistic Investigations of Asymmetric Heck Reactions Proceeding via Neutral Intermediates”
Journal of the American Chemical Society 1998, 120, 6488–6499
A. Ashimori, B. Bachand, M. A. Calter, S. P. Govek, L. E. Overman and D. J. Poon
210. “Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Investigations of Intramolecular Heck Reactions of (E)-,-Unsaturated 2-Haloanilides and Analogs to Form Enantioenriched Spirocyclic Products”
Journal of the American Chemical Society 1998, 120, 6477–6487
A. Ashimori, B. Bachand, L. E. Overman and D. J. Poon
209. “Intramolecular Heck Cyclization of -Sulfenyl Enol Triflates. Asymmetric Synthesis of a Pentacyclic Cardenolide Precursor Having Functionality at C-11”
Tetrahedron Letters 1998, 39, 4647–4650
J. Hynes, Jr., L. E. Overman, T. Nasser and P. V. Rucker
208. “Enantioselective Synthesis of Cardenolide Precursors Using an Intramolecular Heck Reaction”
Tetrahedron Letters 1998, 39, 4643–4646
L. E. Overman and P. V. Rucker
207. “Enantioselective Total Synthesis of Hispidospermidin”
Journal of the American Chemical Society 1998, 120, 4039–4040
L. E. Overman and A. Tomasi
206. “Synthesis of a Phenolic Analog of Aphidicolin. Diminished Stereoselection in Intramolecular 6-Exo Heck Reactions of Substrates Having a Hydrocarbon Tether”
Synlett 1997, 1469–1471
M. M. Abelman, N. Kado, L. E. Overman and A. K. Sarkar
205. “Halide-Terminated N-Acyliminium Ion–Alkyne Cyclizations: A New Construction of Carbacephem Antibiotics”
Journal of Organic Chemistry 1997, 62, 9210–9216
E. Metais, L. E. Overman, M. I. Rodriguez and B. A. Stearns
204. “Pyridinomorphinans: Asymmetric Synthesis of Either Enantiomer and Opioid Receptor Binding Selectivity”
Tetrahedron Letters 1997, 38, 8439–8442
C. Y. Hong, L. E. Overman and A. Romero
203. “An Unexpected Product Arising from Metal Alkylidene Mediated Ring-Closing Diene Metathesis”
Tetrahedron Letters 1997, 38, 8635–8638
D. Joe and L. E. Overman
202. “Cyclopalladated Ferrocenyl Amines as Enantioselective Catalysts for the Rearrangement of Allylic Imidates to Allylic Amides”
Tetrahedron Letters 1997, 38, 8837–8840
T. K. Hollis and L. E. Overman
201. “Total Synthesis of (±)-Scopadulcic Acid B”
Journal of the American Chemical Society 1997, 119, 12031–12040
L. E. Overman, D. J. Ricca and V. D. Tran
200. “Stereocontrolled Synthesis of the Tetracyclic Core of the Bisguanidine Alkaloids Palau'amine and Styloguanidine”
Journal of the American Chemical Society 1997, 119, 7159–7160
L. E. Overman, B. Rogers, J. Tellew and W. C. Trenkle
199. “Ring-Enlarging Cyclohexane Annulations”
Journal of Organic Chemistry 1997, 62, 6379–6387
S. Ando, K. P. Minor and L. E. Overman
198. “Prins-Pinacol Spiroannulations”
Tetrahedron 1997, 53, 8927–8940
K. P. Minor and L. E. Overman
197. “Controlling Stereoselection in Aza-Cope–Mannich Reactions”
Israel Journal of Chemistry 1997, 37, 23–30
L. E. Overman and W. C. Trenkle
196. “Total Synthesis of (+)-Isolaurepinnacin. Use of Acetal–Alkene Cyclizations to Prepare Highly Functionalized Seven-Membered Cyclic Ethers”
Journal of the American Chemical Society 1997, 119, 2446–2452
D. Berger, L. E. Overman and P. A. Renhowe
195. “Allylic Transposition of Alcohol and Amine Functionality by Thermal- or Palladium(II)- Catalyzed Rearrangements of Allylic N-Benzoylbenzimidates”
Journal of Organic Chemistry 1997, 62, 2288–2291
L. E. Overman and G. G. Zipp
194. “First Enantioselective Catalyst for the Rearrangement of Allylic Imidates to Allyl Amides”
Journal of Organic Chemistry 1997, 62, 1449–1456
M. Calter, T. K. Hollis, L. E. Overman, J. Ziller and G. G. Zipp
193. “Intramolecular Heck Reactions in Natural Products Chemistry”
Metal-catalyzed Cross-coupling Reactions, Diederich, F.; Stang, P. J., Eds.; VCH: Weinheim; 1998, Chapter 6, pp 231–269
J. T. Link and L. E. Overman
192. “Aloperine: Stereocontrolled Synthesis of Two Stereoisomers and Determination of Absolute Configuration”
Journal of Organic Chemistry 1997, 62, 440–441
A. D. Brosius and L. E. Overman
191. “Asymmetric Heck Reactions via Neutral Intermediates: Enhanced Enantioselectivity with Halide Additives Gives Mechanistic Insights”
Angewandte Chemie, International Edition in English 1997, 36, 518–521
L. E. Overman and D. J. Poon
190. “Synthesis of 2-Azatricyclo[5.2.1.0]decanes and 2,5-Diazatricyclo[5.2.1]decanes by Intramolecular Azomethine Ylide Cycloadditions”
Journal of Organic Chemistry 1996, 61, 8338–8340
L. E. Overman and J. T. Tellew
189. “A Strategy for Total Synthesis of Complex Cardenolides”
Journal of Organic Chemistry 1996, 61, 6760–6761
W. Deng, M. S. Jensen, L. E. Overman, P. V. Rucker and J.-P. Vionnet
188. “Design and In Vitro Pharmacology of a Selective -Aminobutryic AcidC Receptor Antagonist”
Molecular Pharmacology 1996, 50, 1024–1030
R. M. Woodward, D. Ragozzino, Y. Murata, F. Eusebi, L. E. Overman and R. Miledi
187. “The First Selective Antagonist of the GABAc Receptor”
Bioorganic & Medicinal Chemistry Letters 1996, 6, 2073–2076
Y. Murata, R. M. Woodward, R. Miledi and L. E. Overman
186. “Stereocontrolled Total Syntheses of meso-Chimonanthine and meso-Calycanthine via a Novel Samarium Mediated Reductive Dialkylation”
Journal of the American Chemical Society 1996, 118, 8166–8167
J. T. Link and L. E. Overman
185. “Enantioselective Total Synthesis of (+)-Allopumiliotoxins 267A, 323B and 339A. Application of Iodide-Promoted Iminium Ion–Alkyne Cyclizations for Forming Allopumiliotoxin A Alkaloids”
Journal of the American Chemical Society 1996, 118, 9073–9082
C. Caderas, R. Lett, L. E. Overman, M. H. Rabinowitz, L. A. Robinson, M. J. Sharp and J. Zablocki
184. “Efficient Total Syntheses of Pumiliotoxins A and B. Applications of Iodide-Promoted Iminium Ion–Alkyne Cyclizations in Alkaloid Construction”
Journal of the American Chemical Society 1996, 118, 9062–9072
N. Lin, L. E. Overman, M. H. Rabinowitz, L. A. Robinson, M. J. Sharp and J. Zablocki
183. “Aprotic Chloride and Bromide-Promoted Alkyne-Iminium Ion Cyclizations”
Heterocycles 1996, 42, 549–553
Y. Murata and L. E. Overman
182. “Total Syntheses of Pumiliotoxin A and Allopumiliotoxin Alkaloids. Interplay of Pharmacologically Active Natural Products and New Synthetic Methods and Strategies”
Chemical Reviews 1996, 96, 505–522
A. Franklin and L. E. Overman
181. “New Reactions for Forming Heterocycles and Their Use in Natural Products Synthesis”
Aldrichimica Acta 1995, 28, 107–120
L. E. Overman
180. “Silyl Ethers of Cycloheptene – Novel Proton Pump Inhibitors Obtained During the Total Synthesis of the Scopadulcic Acids”
Bioorganic & Medicinal Chemistry Letters 1995, 5, 2943–2946
T. Hayashi, T. Sugimoto, N. Takewaki, N. Takeguchi, V. Tran, S. O'Connor, P. Rucker and L. E. Overman
179. “Enantioselective Total Synthesis of (–)-7-Deacetoxyalcyonin Acetate. The First Synthesis of a Eunicellin Diterpene”
Journal of the American Chemical Society 1995, 117, 10391–10392
D. W. C. MacMillan and L. E. Overman
178. “Mannich Biscyclizations. Total Synthesis of (–)-Ajmalicine”
Journal of the American Chemical Society 1995, 117, 9139–9150
M. Lögers, L. E. Overman and G. Welmaker
177. “Total Synthesis of (+)-Laurencin. Use of Acetal–Vinylsulfide Cyclizations for Forming Highly Functionalized Eight-Membered Cyclic Ethers”
Journal of the American Chemical Society 1995, 117, 5958–5966
M. Bratz, W. H. Bullock, L. E. Overman and T. Takemoto
176. “The Enantiomer of Strychnine is a Weak Antagonist of the Inhibitory Glycine Receptor”
Bioorganic & Medicinal Chemistry Letters 1995, 5, 749–752
S. D. Knight, R. Miledi, Q.-T. Nguyen, L. E. Overman and G. Pairaudeau
175. “Asymmetric Total Syntheses of (–)- and (+)-Strychnine and the Wieland–Gumlich Aldehyde”
Journal of the American Chemical Society 1995, 117, 5776–5788
S. D. Knight, L. E. Overman and G. Pairaudeau
174. “Enantioselective Total Synthesis of (–)-Ptilomycalin A”
Journal of the American Chemical Society 1995, 117, 2657–2658
L. E. Overman, M. H. Rabinowitz and P. A. Renhowe
173. “Enantioselective Total Synthesis of Either Enantiomer of the Antifungal Antibiotic Preussin (L-657,398) from (S)-Phenylalanine”
Journal of the American Chemical Society 1994, 116, 11241–11250
W. Deng and L. E. Overman
172. “Preparation of Spirocyclic Polyethers by Intramolecular Heck Reactions”
Heterocycles 1994, 39, 497–501
S. D. Knight and L. E. Overman
171. “Regioselective Opening of Terminal Epoxides with 2-(Trialkylsilyl)allyl Organometallic Reagents”
Journal of Organic Chemistry 1994, 59, 4138–4142
L. E. Overman and P. A. Renhowe
170. “An Enantioselective Approach to the Synthesis of Manzamine A”
Tetrahedron Letters 1994, 35, 4279–4282
T. M. Kamenecka and L. E. Overman
169. “Preparation of Opium Alkaloids by Palladium Catalyzed Bis-Cyclizations. Formal Total Synthesis of Morphine”
Tetrahedron Letters 1994, 35, 3453–3456
C. Y. Hong and L. E. Overman
168. “A Convenient Method for the Preparation of 3-Substituted Glutarate Diesters”
Journal of Organic Chemistry 1994, 59, 1946
G. Leotta, III, L. E. Overman and G. S. Welmaker
167. “Application of Intramolecular Heck Reactions for Forming Congested Quaternary Carbon Centers in Complex Molecule Total Synthesis”
Pure and Applied Chemistry 1994, 66, 1423–1430
L. E. Overman
166. “Application of Intramolecular Heck Reactions to the Preparation of Steroid and Terpene Intermediates Having cis A-B Ring Fusions. Model Studies for the Total Synthesis of Complex Cardenolides”
Tetrahedron (Symposium in Print “Palladium in Organic Synthesis”) 1994, 50, 347–358
S. Laschat, F. Narjes and L. E. Overman
165. “Asymmetric Synthesis of Either Enantiomer of Opium Alkaloids and Morphinans. Total Synthesis of (–)- and (+)-Dihydrocodeinone and (–)- and (+)-Morphine”
Journal of the American Chemical Society 1993, 115, 11028–11029
C. Y. Hong, N. Kado and L. E. Overman
164. “Simple Method for Controlling Stereoselection in Mannich Cyclization Reactions of Aldehydes”
Journal of Organic Chemistry 1993, 58, 6947–6948
D. A. Heerding, C. Y. Hong, N. Kado, G. C. Look and L. E. Overman
163. “Enantioselective Total Synthesis of (–)-Strychnine”
Journal of the American Chemical Society 1993, 115, 9293–9294
S. D. Knight, L. E. Overman and G. Pairaudeau
162. “Total Synthesis of (±)-Scopadulcic Acid A. An Illustration of the Utility of Palladium Catalyzed Polyene Cyclizations”
Journal of Organic Chemistry 1993, 58, 5304–5306
D. J. Kucera, S. J. O'Connor and L. E. Overman
161. “Catalytic Asymmetric Synthesis of Either Enantiomer of Physostigmine. Formation of Quaternary Carbon Centers with High Enantioselection by Intramolecular Heck Reactions of (Z)-2-Butenanilides”
Journal of Organic Chemistry 1993, 58, 6949–6951
A. Ashimori, T. Matsuura, L. E. Overman and D. J. Poon
160. “Charge as a Key Component in the Design of New Cyclization Reactions”
Abstract, 33rd National Organic Symposium 1993, 96–116
L. E. Overman
159. “Enantioselective Total Synthesis of (–)-Isolaurepinnacin”
Journal of the American Chemical Society 1993, 115, 9305–9306
D. Berger, L. E. Overman and P. A. Renhowe
158. “First Total Synthesis of Scopadulcic Acid B. An Illustration of the Utility of Palladium- Catalyzed Polyene Cyclizations”
Organometallic Reagents in Organic Synthesis, Academic Press: New York, 1994, pp 117–128
L. E. Overman, M. M. Abelman, D. J. Ricca and V. D. Tran
157. “Preparation of Enantioenriched Tetrahydropyridines by Iminium Ion–Vinylsilane Cyclizations”
Tetrahedron Letters 1993, 34, 5243–5246
P. Castro, L. E. Overman, X. Zhang and P. S. Mariano
156. “Introduction of the 2-Phenylthioethyl, 2-Phenylsulfinylethyl, and 2,2-Di(phenylthio)ethyl Substituents into Cyclic Ketones”
Journal of Organic Chemistry 1993, 58, 6476–6479
J. Montgomery and L. E. Overman
155. “Studies Towards the Total Synthesis of (+)-Ptilomycalin A. Use of a Tethered Biginelli Condensation for the Preparation of an Advanced Tricyclic Intermediate”
Journal of Organic Chemistry 1993, 58, 3235–3237
L. E. Overman and M. H. Rabinowitz
154. “Total Synthesis of Amaryllidaceae Alkaloids of the 5,11-Methanomorphanthride Type. Efficient Total Syntheses of (–)-Pancracine and (±)-Pancracine”
Journal of Organic Chemistry 1993, 58, 4662–4672
L. E. Overman and J. Shim
153. “First Total Synthesis of Lycopodium Alkaloids of the Magellenane Group. Enantioselective Total Syntheses of (–)-Magellanine and (+)-Magellaninone”
Journal of the American Chemical Society 1993, 115, 2992–2993
G. C. Hirst, T. O. Johnson and L. E. Overman
152. “The Aza-Cope-Mannich Approach to Strychnos Alkaloids. Short Stereocontrolled Total Syntheses of (±)-Dehydrotubifoline and (±)-Akuammicine”
Journal of the American Chemical Society 1993, 115, 3966–3976
S. R. Angle, J. M. Fevig, S. D. Knight, R. M. Marquis, Jr. and L. E. Overman
151. “General Approach to Halogenated Tetrahydrofuran Natural Products from Red Algae of the Genus Laurencia. The Total Synthesis of (±)-Kumausallene and (±)-epi-Kumausallene”
Journal of Organic Chemistry 1993, 58, 2468–2477
T. A. Grese, K. D. Hutchinson and L. E. Overman
150. “Total Synthesis of the Amaryllidaceae Alkaloid (±)-Epielwesine. The Importance of Vinylsilane Stereochemistry in Iminium Ion–Vinylsilane Cyclizations”
Heterocycles 1993, 35, 205–225
R. M. Burk and L. E. Overman
149. “First Total Synthesis of Scopadulcic Acid B”
Journal of the American Chemical Society 1993, 115, 2042–2044
L. E. Overman, D. J. Ricca and V. D. Tran
148. “Preparation of Unsaturated Seven and Eight Membered Nitrogen Heterocycles by Iodide-Promoted Alkyne–Iminium Ion Cyclizations”
Synlett 1992, 995–996
I. M. Rodriguez-Campos and L. E. Overman
147. “Preparation of Seven-Membered Cyclic Ethers Containing Halogenated Side Chains by Acetal-Alkene Cyclizations”
Synlett 1992, 811–812
D. Berger and L. E. Overman
146. “Palladium-Catalyzed Polyene Cyclizations”
Pure and Applied Chemistry 1992, 64, 1813–1819
L. E. Overman, M. M. Abelman, D. J. Kucera, D. J. Ricca and V. D. Tran
145. “Controlling Stereoselection in Intramolecular Heck Reactions by Tailoring the Palladium Catalyst”
Tetrahedron Letters 1992, 33, 4859–4862
A. Madin and L. E. Overman
144. “Iodide-Promoted Aldiminium Ion–Alkyne Cyclizations. A Convenient Synthesis of Substituted Tetrahydropyridines and 3-Alkyldenepiperidines”
Tetrahedron Letters 1992, 33, 4103–4106
L. E. Overman and A. K. Sarkar
143. “Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Palladium Catalyzed Formation of Either Enantiomer of Spirooxindoles and Related Spirocyclics Using a Single Enantiomer of a Chiral Diphosphine Ligand”
Journal of Organic Chemistry 1992, 57, 4571–4572
A. Ashimori and L. E. Overman
142. “Charge as a Key Component in Reaction Design. The Invention of Cationic Cyclization Reactions of Importance in Synthesis”
Accounts of Chemical Research 1992, 25, 352–359
L. E. Overman
141. “Reaction of Na2Fe(CO)4 with an Unsaturated Aziridinium Ion. Unprecedented Rearrangement of an Alkyltetracarbonylferrate Intermediate”
Journal of Organic Chemistry 1992, 57, 1035–1038
L. E. Overman and M. J. Sharp
140. “Synthesis of 3-Acyl-3-Alkyloxindoles”
Tetrahedron Letters 1991, 32, 6993–6996
C. J. Flann, L. E. Overman and A. Sarkar
139. “First Total Synthesis of (+)-Allopumiliotoxin 339A. A Practical Entry to Dendrobatid Alkaloids of the Allopumiliotoxin Class”
Journal of the American Chemical Society 1992, 114, 368–369
L. E. Overman, L. A. Robinson and J. Zablocki
138. “Ring-Enlarging Cyclopentene Annulations”
Tetrahedron Letters 1991, 32, 7361–7364
T. Johnson and L. E. Overman
137. “First Total Synthesis of Amaryllidaceae Alkaloids of the 5,11-Methanomorphanthridine Type. An Efficient Total Synthesis of (±)-Pancracine”
Journal of Organic Chemistry 1991, 56, 5005–5007
L. E. Overman and J. Shim
136. “New Approach to Strychnos Alkaloids. Stereocontrolled Total Synthesis of (±)-Dehydrotubifoline”
Journal of the American Chemical Society 1991, 113, 5085–5086
J. M. Fevig, R. M. Marquis, Jr. and L. E. Overman
135. “The First Enantioselective Total Syntheses of the Allopumiliotoxin A Alkaloids 267A and 339B”
Journal of Organic Chemistry 1992, 57, 1179–1190
S. W. Goldstein, L. E. Overman, and M. H. Rabinowitz
134. “3(S)-((tert-Butyldiphenylsilyl)oxy)-2-butanone (2-Butanone, (S)-3-[[1,1-dimethylethyl)diphenylsilyl]]oxy]”
Organic Syntheses 1992, 71, 56–62; Collective Volume IX, p 139–142
L. E. Overman and G. M. Rishton
133. “Stereocontrolled Preparation of 3-Acyltetrahydrofurans from Acid-Promoted Rearrangements of Allylic Ketals: (2S,3S)-3-Acetyl-8-carboethoxy-2,3-dimethyl-1-oxa-8-azaspiro[4.5]decane”
Organic Syntheses 1992, 71, 63–71; Collective Volume IX, pp 4–9
L. E. Overman and G. M. Rishton
132. “General Approach to Halogenated Tetrahydrofuran Natural Products from Red Algae of the Genus Laurencia. Total Synthesis of (±)-trans-Kumausyne and Demonstration of an Asymmetric Synthesis Strategy”
Journal of the American Chemical Society 1991, 113, 5378–5384
M. J. Brown, T. Harrison and L. E. Overman
131. “Stereocontrolled Preparation of Tetrahydrofurans from Acid-Promoted Rearrangements of Allylic Acetals”
Journal of the American Chemical Society 1991, 113, 5354–5365
M. H. Hopkins, L. E. Overman and G. M. Rishton
130. “Acid-Promoted Reaction of Cyclic Allylic Diols with Carbonyl Compounds. Stereoselective Ring-Enlarging Tetrahydrofuran Annulations”
Journal of the American Chemical Society 1991, 113, 5365–5378
M. J. Brown, T. Harrison, P. M. Herrinton, M. H. Hopkins, K. D. Hutchinson, P. Mishra and L. E. Overman
129. “Use of Aza-Cope Rearrangement–Mannich Cyclization Reactions to Achieve a General Entry to Melodinus and Aspidosperma Alkaloids. Stereocontrolled Total Syntheses of (±)-Deoxoapodine, (±)-Meloscine, and (±)-Epimeloscine and a Formal Synthesis of 1-Acetylaspidoalbidine”
Journal of the American Chemical Society 1991, 113, 2598–2610
L. E. Overman, G. M. Robertson and A. J. Robichaud
128. “Preparation of 3-Amino-4-(hydroxymethyl)azetidin-2-ones from the Reaction of Glycine Enolates with Imines of a Glycoaldehyde”
Journal of Organic Chemistry 1991, 56, 1933–1936
M. J. Brown and L. E. Overman
127. “Construction of Quaternary Carbon Centers by Palladium-Catalyzed Intramolecular Alkene Insertions. Total Synthesis of the Amaryllidaceae Alkaloids ()-Tazettine and ()-6a-Epipretazettine”
Journal of the American Chemical Society 1990, 112, 6959–6964
M. M. Abelman, L. E. Overman and V. D. Tran
126. “Formation of 4-Oxocenes from Lewis Acid-Promoted Cyclization of 5-Hexenyl Acetals. Evidence for a Concerted Ene Cyclization Mechanism”
Journal of the American Chemical Society 1990, 112, 4399–4403
T . A. Blumenkopf, G. C. Look and L. E. Overman
125. “Preparation of Eight-Membered Cyclic Ethers by Lewis Acid Promoted Acetal–Alkene Cyclizations”
Journal of the American Chemical Society 1990, 112, 4386–4399
T. A. Blumenkopf, M. Bratz, A. Castañeda, G. C. Look, L. E. Overman, D. Rodriguez and A. S. Thompson
124. “Mechanism of the Palladium Dichloride Catalyzed Cope Rearrangement of Acyclic Dienes. A Substituent Effect Study”
Journal of the American Chemical Society 1990, 112, 3945–3949
L. E. Overman and A. F. Renaldo
123. “Palladium-Catalyzed Polyene Cyclizations of Trienyl Triflates”
Journal of Organic Chemistry 1989, 54, 5846–5848
N. E. Carpenter, D. J. Kucera and L. E. Overman
122. “Pumiliotoxin Alkaloids: A New Class of Sodium Channel Agents”
Biochemical Pharmacology 1990, 40, 315–326
J. W. Daly, F. Gusovsky, E. T. McNeal, S. Secunda, M. Bell, C. R. Creveling, Y. Nishizawa, L. E. Overman, M. J. Sharp and D. P. Rossignol
121. “Intramolecular (N-Acyloxy)iminium Ion-Alkyne Cycloadditions. A New Route to Bicyclic -Amino Ketones”
Journal of Organic Chemistry 1990, 55, 1447–1459
M. J. Fisher and L. E. Overman
120. “Intramolecular Mannich and Related Reactions”
Comprehensive Organic Synthesis 1991, 2, 1007–1046
L. E. Overman and D. J. Ricca
119. “(E)-1-Benzyl-3-(1-iodoethylidene)piperidine. Nucleophile-Promoted Alkyne Iminium Ion Cyclizations”
Organic Syntheses 1991, 70, 111–119; Collective Volume IX, pp 46–51
H. J. Arnold, L. E. Overman, M. J. Sharp and M. C. Witschel
118. “Total Synthesis of ()-Meloscine and ()-Epimeloscine”
Journal of Organic Chemistry 1989, 54, 1236–1238
L. E. Overman, G. M. Robertson and A. J. Robichaud
117. “Stereocontrolled Construction of Carbocyclic Rings by Sequential Cationic Cyclization–Pinacol Rearrangements”
Journal of the American Chemical Society 1989, 111, 1514–1515
G. C. Hirst, P. N. Howard and L. E. Overman
116. “Cationic Cyclization Reactions Terminated by Pinacol Rearrangements”
Selectivities in Lewis Acid-Promoted Reactions, NATO ASSI Series, Kluwer Academic: Dordrecht, Netherlands, Vol. 289; D. Schinzer, Ed.; 1989, pp 1–20
L. E. Overman
115. “Preparation of Seven-Membered Ring Cyclic Ethers and 3-Alkylidene-Tetrahydropyrans from the Cyclization of Oxonium Cations Derived from Unsubstituted and Silicon-Containing 4-Alken-1-ols”
Journal of Organic Chemistry 1989, 54, 5695–5707
A. Castañeda, D. J. Kucera and L. E. Overman
114. “Preparation of Functionalized Hydroindol-3-ols via Tandem Aza-Cope Rearrangement–Mannich Cyclizations. Formal Total Synthesis of (+)-6a-Epipretazettine and Related Alkaloids”
Tetrahedron Letters 1989, 30, 647–650
L. E. Overman and H. Wild
113. “Synthesis of Allopumiliotoxin A Alkaloids via Iminium Ion–Vinylsilane Cyclizations"
Tetrahedron Letters 1988, 29, 6541–6544
R. M. Lett, L. E. Overman and J. Zablocki
112. “Complementary Use of Iminium Ion and Acyl Iminium Ion Cyclization Initiators for Asymmetric Synthesis of Both Enantiomers of Hydroxylated Indolizidines”
Journal of Organic Chemistry 1989, 54, 2591–2596
M.-P. Heitz and L. E. Overman
111. “Total Syntheses of (+)-Geissoschizine, (±)-Geissoschizine, and (±)-(Z)-Isositsirikine. Stereocontrolled Synthesis of Exocyclic Double Bonds by Stereospecific Iminium Ion–Vinylsilane Cyclizations”
Journal of the American Chemical Society 1989, 111, 300–308
L. E. Overman and A. J. Robichaud
110. “Synthesis Studies Directed Towards Gelsemine. Preparation of an Advanced Pentacyclic Intermediate”
Tetrahedron Letters 1988, 29, 3785–3788
W. G. Earley, T. Oh and L. E. Overman
109. “Synthesis Studies Directed Towards Gelsemine. A New Synthesis of Highly Functionalized cis-Hydroisoquinolines”
Tetrahedron Letters 1988, 29, 3781–3784
W. G. Earley, E. J. Jacobsen, G. P. Meier, T. Oh and L. E. Overman
108. “Studies on the Total Synthesis of Gelsemine”
Proceedings of the First Princess Chulabhorn Science Congress 1987. International Congress on Natural Products 1990, 3, 381–390
W. G. Earley, E. J. Jacobsen, T. Oh and L. E. Overman
107. “Synthesis of Substituted Tetrahydropyridines by Cyclizations of Silicon-Containing Iminium Ions”
Tetrahedron (Symposium in Print) 1988, 44, 3919–3930
G. W. Daub, D. A. Heerding and L. E. Overman
106. “Palladium-Catalyzed Polyene Cyclizations of Dienyl Aryl Iodides”
Journal of the American Chemical Society 1988, 110, 2328–2329
M. M. Abelman and L. E. Overman
105. “Enantioselective Total Synthesis of the Pumiliotoxin A Alkaloids via Reductive Iminium Ion–Alkyne Cyclizations. Total Synthesis of (+)-Pumiliotoxin A”
Tetrahedron Letters 1988, 29, 901–904
L. E. Overman and M. J. Sharp
104. “Synthesis and Diels-Alder Reactions of 5-Alkenyl-1,3-Oxathiole-3-Oxides. A New Class of Diheterosubstituted 1,3-Dienes”
Journal of Organic Chemistry 1988, 53, 2630–2634
M. J. Fisher and L. E. Overman
103. “Nucleophile-Promoted Electrophilic Cyclization Reactions of Alkynes”
Journal of the American Chemical Society 1988, 110, 612–614, 5934
L. E. Overman and M. J. Sharp
102. “Total Synthesis of (–)-Laurenyne. The Use of Acetal-Initiated Cyclizations to Prepare Functionalized Eight-Membered Cyclic Ethers”
Journal of the American Chemical Society 1988, 110, 2248–2256
L. E. Overman and A. S. Thompson
101. “Face Selectivity in Diels–Alder Reactions of Chiral Dienes Containing Allylic Substituents”
Journal of the American Chemical Society 1988, 110, 4625–4633
M. J. Fisher, W. J. Hehre, S. D. Kahn and L. E. Overman
100. “Scope and Mechanism of Tandem Cationic Aza-Cope Rearrangement–Mannich Cyclization Reactions”
Journal of the American Chemical Society 1988, 110, 4329–4336
E. J. Jacobsen, J. Levin and L. E. Overman
99. “Enantioselective Total Synthesis of Streptazolin. The Tandem Use Iminium Ion–Vinylsilane Cyclizations and Intramolecular Acylations”
Journal of the American Chemical Society 1987, 109, 6115–6119
C. J. Flann and L. E. Overman
98. “Medium Effects and the Nature of the Rate-Determining Step in Mannich-Type Cyclizations”
Journal of the American Chemical Society 1987, 109, 6107–6114
S. J. McCann and L. E. Overman
97. “Intramolecular Alkene Arylations for Rapid Assembly of Polycyclic Systems Containing Quaternary Centers. A New Synthesis of Spirooxindoles and Other Fused and Bridged Ring Systems”
Journal of Organic Chemistry 1987, 52, 4130–4133
M. M. Abelman, T. Oh and L. E. Overman
96. “Ring-Enlarging Furan Annulations”
Journal of Organic Chemistry 1987, 52, 3711–3712
P. M. Herrinton, M. H. Hopkins, P. Mishra, M. J. Brown and L. E. Overman
95. “A Naturally Occurring Erythro Diastereomer of Pumiliotoxin B”
Tetrahedron 1988, 44, 6795–6800
H. M. Garraffo, M. W. Edwards, T. F. Spande, J. W. Daly, L. E. Overman, C. Severini and V. Erspamer
94. “Stereocontrolled Preparation of Tetrahydrofurans by Acid-Catalyzed Rearrangement of Allylic Acetals”
Journal of the American Chemical Society 1987, 109, 4748–4749
M. H. Hopkins and L. E. Overman
93. “Pumiliotoxin Alkaloids: Relationship of Cardiotonic Activity to Sodium Channel Activity and Phosphatidylinositol Turnover”
Journal of Medicinal Chemistry 1988, 31, 477–480
J. W. Daly, E. McNeal, F. Gusovsky, F. Ito and L. E. Overman
92. “Transition State Geometry of [3,3]-Sigmatropic Rearrangements of Iminium Ions”
Journal of Organic Chemistry 1988, 53, 685–690
R. J. Doedens, G. P. Meier and L. E. Overman
91. “Cationic Cyclization Reactions of Vinylsilanes in Heterocyclic Synthesis”
Chemica Scripta 1987, 27, 543–544
L. E. Overman
90. “Iminium Ion and Acyliminium Ion Initiated Cyclization Reactions of Vinylsilanes. Regiocontrolled Synthesis of Tetrahydropyridines and Related Heterocycles”
Journal of the American Chemical Society 1987, 109, 6097–6107
C. Flann, T. C. Malone and L. E. Overman
89. “tert-Butyldiphenylsilylamines: Useful Protecting Groups for Primary Amines”
Tetrahedron Letters 1986, 27, 4301–4304
L. E. Overman, M. E. Okazaki and P. Mishra
88. “Efficient Preparations of 8- and 9-Membered Cyclic Ethers”
Journal of the American Chemical Society 1986, 108, 3516–3517
L. E. Overman, T. A. Blumenkopf, A. Castañeda and A. S. Thompson
87. “Regioselective Synthesis of Tetrahydropyridines. Synthesis of 1-(4-Methoxyphenyl)-1,2,5,6-tetrahydropyridine”
Organic Syntheses 1989, 68, 188–197; Collective Volume VIII, pp 358–362
L. E. Overman, C. J. Flann and T. C. Malone
86. “Vinylsilane- and Alkynylsilane-Terminated Cyclization Reactions”
Chemical Reviews 1986, 86, 857–873
T. A. Blumenkopf and L. E. Overman
85. “Heterocyclization Reactions Employing Vinylsilane Terminators”
Lectures in Heterocyclic Chemistry 1985, 8, 59–67
L. E. Overman
84. “Acetal-Initiated Cyclizations of Vinylsilanes. A General Synthesis of Allylically Unsaturated Oxacyclics”
Journal of the American Chemical Society 1986, 108, 1303–1304
L. E. Overman, A. Castañeda and T. A. Blumenkopf
83. “Modeling Chemical Reactivity 1. Regioselectivity of Diels–Alder Cycloadditions of Electron-Rich Dienes with Electron-Deficient Dienophiles”
Journal of the American Chemical Society 1986, 108, 7381–7396
S. D. Kahn, C. F. Pau, L. E. Overman and W. J. Hehre
82. “Enantioselective Total Synthesis of (+)-Pumiliotoxin A”
Journal of Organic Chemistry 1985, 50, 3669–3670
L. E. Overman and N.-H. Lin
81. “The Synthesis of Indolizidines by Intramolecular Ene Cyclizations. Preparation of (E)-Alkylidene Analogs of Pumiliotoxin A”
Tetrahedron Letters 1985, 26, 4167–4170
L. E. Overman and D. Lesuisse
80. “(Z)-4-(Trimethylsilyl)-3-buten-1-ol”
Organic Syntheses 1989, 68, 182–187; Collective Volume VIII, pp 609–612
L. E. Overman, M. J. Brown and S. F. McCann
79. “Stereocontrolled Synthesis of Substituted cis-Cyclopenta[b]pyrrolidines”
Journal of Organic Chemistry 1985, 50, 2403–2405
L. E. Overman, M. Okazaki and E. J. Jacobsen
78. “Synthesis Applications of Cationic Aza-Cope Rearrangements. Stereocontrolled Synthesis of Hexahydro-1H-pyrrolo[2,3-d]carbazoles”
Journal of Organic Chemistry 1985, 50, 4021–4028
L. E. Overman and S. R. Angle
77. “A Convenient Synthesis of 1-Pyrrolines and 1-Piperideines”
Tetrahedron Letters 1984, 25, 5737–5738
L. E. Overman and R. M. Burk
76. “The Importance of Vinylsilane Stereochemistry and - Stabilization in Iminium Ion–Vinylsilane Cyclizations. A Short Total Synthesis of the Amaryllidaceae Alkaloid (±)-Epielwesine”
Tetrahedron Letters 1984, 25, 5739–5742
L. E. Overman and R. M. Burk
75. “A Convenient Method for Obtaining trans-2-Aminocyclohexanol and trans-2-Aminocyclopentanol in Enantiomerically Pure Form”
Journal of Organic Chemistry 1985, 50, 4154–4155
L. E. Overman and S. Sugai
74. “Total Synthesis of (–)-Crinine. Use of Tandem Cationic Aza-Cope Rearrangement/ Mannich Cyclizations for the Synthesis of Enantiomerically Pure Amaryllidaceae Alkaloid”
Helvetica Chimica Acta 1985, 68, 745–749
L. E. Overman and S. Sugai
73. “A Convenient Synthesis of 4-Unsubstituted -Lactams”
Journal of the American Chemical Society 1985, 107, 1698–1701
L. E. Overman and T. Osawa
72. “Enantioselective Total Synthesis of Allopumiliotoxin A Alkaloids 267A and 339B”
Journal of the American Chemical Society 1984, 106, 5360–5361
L. E. Overman and S. W. Goldstein
71. “A Convenient Synthesis of Unsymmetrical Secondary Amines. In Situ Formation of Unstable Formaldehyde Imines”
Tetrahedron Letters 1984, 25, 1635–1638
L. E. Overman and R. M. Burk
70. “A New Class of Cardiotonic Agents: Structure-Activity Correlations for Natural and Synthetic Analogs of the Alkaloid Pumiliotoxin B”
Journal of Medicinal Chemistry 1985, 28, 482–486
J. W. Daly, E. T. McNeal, L. E. Overman and D. H. Ellison
69. “Mercury(II) and Palladium(II)-Catalyzed [3,3]-Sigmatropic Rearrangements”
Angewandte Chemie, International Edition in English 1984, 23, 579–586
L. E. Overman
68. “New Synthetic Route to Perhydrohistrionicotoxin Using (3Z)-4-Butyl-3-Trichloroacetamido-1,3-Butadiene”
Heterocycles 1984, 22, 485–488
T. Ibuka, H. Minakata, M. Hashimoto, L. E. Overman and R. L. Freerks
67. “Recent Advances in the Total Synthesis of Pentacyclic Aspidosperma Alkaloids”
Alkaloids: Chemical and Biological Perspectives” S. W. Pelletier, Ed., Volume 3, 1985, pp 275–307
L. E. Overman and M. Sworin
66. “Iminium Ion and Acyliminium Ion Initiated Cyclizations of Vinylsilanes. Regiocontrolled Construction of Unsaturated Azacyclics”
Journal of the American Chemical Society 1983, 105, 6993–6994
L. E. Overman, T. C. Malone and G. P. Meier
65. “Enantioselective Total Syntheses of Pumiliotoxin B and Pumiliotoxin 251D. A General Entry to the Pumiliotoxin A Alkaloids via Stereospecific Iminium Ion-Vinylsilane Cyclizations”
Journal of the American Chemical Society 1984, 106, 4192–4201
L. E. Overman, K. L. Bell and F. Ito
64. “Palladium Dichloride Catalyzed Cope Rearrangements of Functionalized Acyclic 1,5-Dienes”
Tetrahedron Letters 1983, 24, 3757–3760
L. E. Overman and A. F. Renaldo
63. “Synthesis Applications of Cationic Aza-Cope Rearrangements. Stereoselective Synthesis of cis- and trans-3a-Aryl-4-oxodecahydrocyclohepta[b]pyrroles”
Journal of Organic Chemistry 1983, 48, 3393–3400
L. E. Overman, E. J. Jacobsen and R. J. Doedens
62. “Applications of Cationic Aza-Cope Rearrangements for Alkaloid Synthesis. Stereoselective Preparation of cis-3a-Arylhydroindoles and a New Short Route to Amaryllidaceae Alkaloids”
Journal of the American Chemical Society 1983, 105, 6629–6637
L. E. Overman, L. T. Mendelson and E. J. Jacobsen
61. “Carbon–Carbon Bond Formation Under Mild Conditions via Tandem Cationic Aza-Cope–Mannich Reactions. A Convenient Synthesis of Polysubstituted Pyrrolidines”
Journal of the American Chemical Society 1983, 105, 6622–6629
L. E. Overman, M. Kakimoto, M. Okazaki and G. P. Meier
60. “Palladium Dichloride Promoted Cyclizations of 1,5-Dienes. A New Method for Forming Cyclohexenes”
Tetrahedron Letters 1983, 24, 2235–2238
L. E. Overman and A. F. Renaldo
59. “Importance of Allylic Interactions and Stereoelectronic Effects in Dictating the Steric Course of the Reaction of Iminium Ions with Nucleophiles. An Efficient Total Synthesis of (+)-Gephyrotoxin”
Journal of the American Chemical Society 1983, 105, 5373–5379
L. E. Overman, D. Lesuisse and M. Hashimoto
58. “Preparation and Diels-Alder Reactions of 1,3-Dienes Containing Both Sulfur and Nitrogen Substituents. Complete Orientational Control by the Acylamino Group”
Journal of the American Chemical Society 1983, 105, 6335–6337
L. E. Overman, C. B. Petty, T. Ban and G. T. Huang
57. “Carbonyl Participation in the Reaction of N-Acyl-2-isopropenylpyrrolidines with Halogen Electrophiles. Stereocontrolled Preparation of Enantiomerically Pure Synthons for the Synthesis of Pumiliotoxin A Alkaloids”
Tetrahedron Letters 1982, 23, 4887–4890
L. E. Overman and R. J. McCready
56. “A New Approach for the Total Synthesis of Pentacyclic Aspidosperma Alkaloids. Total Synthesis of dl-16-Methoxytabersonine”
Journal of Organic Chemistry 1983, 48, 2685–2690
L. E. Overman, M. Sworin and R. M. Burk
55. “Highly Stereocontrolled Reduction of '-Alkoxyenones to Give Either the Threo or Erythro Allylic 1,2-Diol. Assignment of the Threo Configuration to the C-15, C-16 Diol of Pumiliotoxin B”
Tetrahedron Letters 1982, 23, 2355–2358
L. E. Overman and R. J. McCready
54. “The Cyanomethyl Group for Nitrogen Protection and Iminium Ion Generation in Ring-Enlarging Pyrrolidine Annulations. A Short Synthesis of the Amaryllidaceae Alkaloid
dl-Crinine”
Tetrahedron Letters 1982, 23, 2741–2744
L. E. Overman and E. J. Jacobsen
53. “Synthesis Applications of Aza-Cope Rearrangements. Stereocontrolled Synthesis of Cyclohepta[b]pyrroldines”
Tetrahedron Letters 1982, 23, 2737–2740
L. E. Overman and E. J. Jacobsen
52. “Synthesis Applications of Aza-Cope Rearrangements. Stereoselective Synthesis of trans-2-Alkyl-cis-3a-aryloctahydroindolones”
Tetrahedron Letters 1982, 23, 2733–2736
L. E. Overman, L. T. Mendelson and L. A. Flippin
51. “Stereocontrolled Synthesis of Exocyclic Trisubstituted Double Bonds by Stereospecific Iminium Ion–Vinylsilane Cyclizations. A Short Synthetic Route to Indoloquinolizidine Alkaloids”
Journal of Organic Chemistry 1982, 47, 5297–5300
L. E. Overman and T. C. Malone
50. “Chair Topology of the Palladium Dichloride-Catalyzed Cope Rearrangement of Acyclic 1,5-Dienes”
Journal of the American Chemical Society 1982, 104, 7225–7231
L. E. Overman and E. J. Jacobsen
49. “Synthesis Applications of Aza-Cope Rearrangements. A Stereoselective Synthesis of cis-3a-Aryloctahydroindolones and a New Short Entry to Amaryllidaceae Alkaloids”
Journal of the American Chemical Society 1981, 103, 5579–5581
L. E. Overman and L. T. Mendelson
48. “Synthesis Applications of Aza-Cope Rearrangements. A Stereoselective Synthesis of 9a-Arylhydrolilolidines and a New Approach to the Synthesis of Aspidosperma Alkaloids”
Tetrahedron (Symposium in Print) 1981, 37, 4041–4045
L. E. Overman and M. Sworin
47. “A Short Total Synthesis of (+)-Perhydrogephyrotoxin”
Journal of Organic Chemistry 1981, 46, 2833–2835
L. E. Overman and R. L. Freerks
46. “Enantiospecific Total Synthesis of Dendrobatid Toxin 251D. A Short Chiral Entry to the Cardiac-Active Pumiliotoxin A Alkaloids via Stereospecific Iminium Ion–Vinylsilane Cyclizations”
Journal of the American Chemical Society 1981, 103, 1851–1853
L. E. Overman and K. L. Bell
45. “Facile Aminolysis of Epoxides with Diethylaluminum Amides”
Tetrahedron Letters 1981, 22, 195–199
L. E. Overman and L. A. Flippin
44. “Preparation of Substituted 2-Pyridones by Thermal Rearrangement of Propargylic Pseudoureas. Improvements in the 2-Pyridone Yields by Variations of the Pseudourea NR2 Substituent”
Journal of Organic Chemistry 1981, 46, 811–813
L. E. Overman and J. P. Roos
43. “A New Method for Stereoselective Piperidine Annulation. Directing the 2-Azonia-[3,3]-Sigmatropic Rearrangement by Irreversible Hydrolysis”
Journal of Organic Chemistry 1980, 45, 5229–5230
L. E. Overman and T. Yokomatsu
42. “Diels–Alder Reactions of 1-N-Acylamino-1,3-dienes”
Journal of the American Chemical Society 1981, 103, 2816–2822
L. E. Overman, R. L. Freerks, C. B. Petty, L. A. Clizbe, R. K. Ono, G. F. Taylor and P. J . Jessup
41. “Thermal Rearrangements of Propargylic Trichloroacetimidates. Synthesis of Trichloroacetamido-1,3-and 1,2-dienes”
Journal of the American Chemical Society 1981, 103, 2807–2816
L. E. Overman, L. A. Clizbe, R. L. Freerks and C. K. Marlowe
40. “Pumiliotoxin-C and Synthetic Analogs: A New Class of Nicotinic Antagonists”
Molecular Pharmacology 1982, 22, 565–573
Y. Nimitkitpaisan, J. W. Daly, P. J. Jessup, L. E. Overman, J. E. Warnick and E. X. Albuquerque
39. “Allylic and Propargylic Imidic Esters in Organic Synthesis”
Accounts of Chemical Research 1980, 13, 218–224
L. E. Overman
38. “Stereoselective Total Synthesis of (+)-Perhydrogephyrotoxin. Synthetic Applications of Directed 2-Azonia-[3,3]-Sigmatropic Rearrangements”
Journal of the American Chemical Society 1980, 102, 1454–1456
L. E. Overman and C. Fukaya
37. “Palladium(II)Chloride-Catalyzed Cope Rearrangements of Acyclic 1,5-Dienes”
Journal of the American Chemical Society 1980, 102, 865–867
L. E. Overman and F. M. Knoll
36. “Directed 2-Azonia-[3,3]-Sigmatropic Rearrangements. A Convenient Preparation of Substituted 1-Azaspiro[4,5]decanes”
Tetrahedron Letters 1979, 42, 4041–4044
L. E. Overman, M. Kakimoto and M. Okawara
35. “Synthetic Applications of N-Acylamino-1,3-dienes. Control of Endo Stereoselectivity by the Acyl Substituent. A Stereospecific Synthesis of the Analgesic Tilidine”
Journal of Organic Chemistry 1979, 44, 4183–4185
L. E. Overman, C. B. Petty and R. J. Doedens
34. “Preparation of Substituted 2-Pyridones by Thermal Rearrangement of Propargylic Pyrrolidine Pseudoureas”
Journal of the American Chemical Society 1980, 102, 747–754
L. E. Overman, S. Tsuboi, J. P. Roos and G. F. Taylor
33. “4-Methylene-1,5-Dihydrooxazoles: Isolation, Properties and Use for the Preparation of Substituted Oxazoles”
Journal of Organic Chemistry 1979, 44, 2323–2325
L. E. Overman, S. Tsuboi and S. Angle
32. “The Preparation of Trichloroacetamido-1,2-dienes”
Tetrahedron Letters 1979, 20, 599–603
L. E. Overman, C. M. Marlowe and L. A. Clizbe
31. “Palladium(II)-Catalyzed Rearrangement of Allylic Acetates”
Tetrahedron Letters 1979, 20, 321–324
L. E. Overman and F. M. Knoll
30. “Carbon–Carbon Bond Formation via Directed 2-Azonia-[3,3]-Sigmatropic Rearrangements. A New Pyrrolidine Synthesis”
Journal of the American Chemical Society 1979, 101, 1310–1313
L. E. Overman and M. Kakimoto
29. “Preparation of Rearranged Allylic Isocyanates from the Reaction of Allylic Alkoxides with Cyanogen Chloride”
Journal of Organic Chemistry 1978, 43, 4564–4567
L. E. Overman and M. Kakimoto
28. “Synthetic Applications of N-Acylamino-1,3-dienes. An Efficient Stereospecific Total Synthesis of dl-Pumiliotoxin C and a General Entry to cis-Decahydroquinoline Alkaloids”
Journal of the American Chemical Society 1978, 100, 5179–5185
L. E. Overman and P. J. Jessup
27. “How Important is Secondary Orbital Overlap in Determining the Regioselectivity of Diels–Alder Reactions?”
Tetrahedron Letters 1978, 19, 1313–1316
I. Fleming, J. P. Michael, L. E. Overman and G. F. Taylor
26. “trans-1-N-Acylamino-1,3-dienes: Preparation from Dienoic Acids”
Journal of Organic Chemistry 1978, 43, 2164–2167
L. E. Overman, G. F. Taylor, C. B. Petty and P. J. Jessup
25. “Mild Procedures for Interconverting Allylic Oxygen Functionality. Cyclization-Induced [3,3]-Sigmatropic Rearrangement of Allylic Carbamates”
Journal of the American Chemical Society 1978, 100, 4822–4834
L. E. Overman, C. B. Campbell and F. M. Knoll
24. “1-N-Acylamino-1,3-dienes from 2,4-Pentadienoic Acids by the Curtius Rearrangement: Benzyl trans-1,3-Butadiene-1-carbamate”
Organic Syntheses 1979, 59, 1–9; Collective Volume VI, pp 95–101
P. J. Jessup, C. B. Petty, J. Roos and L. E. Overman
23. “The Diels–Alder Reaction Between trans-1-N-Acylamino-1,3-dienes and Methyl Acrylate. A Correlation Between Diene Photoelectron Ionization Potentials and Reactivity, Stereoselectivity and Regioselectivity”
Journal of the American Chemical Society 1978, 100, 3182–3189
L. E. Overman, G. F. Taylor, K. N. Houk and L. S. Domelsmith
22. “A Short Stereospecific Total Synthesis of dl-Pumiliotoxin C”
Tetrahedron Letters 1977, 18, 1253–1256
L. E. Overman and P. J. Jessup
21. “A New Synthesis of 2-Pyridones. Solution Thermolysis of Propargylic Pseudoureas”
Journal of the American Chemical Society 1977, 99, 2813–2815
L. E. Overman and S. Tsuboi
20. “Gas Phase Acidities of the 2-Butenes. Regarding the Use of Organometallics as Models for Free Carbanions”
Journal of the American Chemical Society 1977, 99, 1976–1977
J. E. Bartmess, W. J. Hehre, R. T. McIver, Jr. and L. E. Overman
19. “Mercury(II)-Catalyzed 3,3-Sigmatropic Rearrangements of Allylic N,N-Dimethylcarbamates: A Mild Method for Allylic Equilibrations and Contrathermodynamic Allylic Isomer Enrichments”
Journal of Organic Chemistry 1976, 41, 3338–3340
L. E. Overman and C. B. Campbell
18. “N-Acyl-1-amino-1,3-dienes: 1-Amino-1,3-diene Synthetic Equivalents for the Diels-Alder Reaction”
Tetrahedron Letters 1976, 17, 3089–3092
L. E. Overman, G. F. Taylor and P. J. Jessup
17. “The Preparation of Ureas by the Thermolysis of Allylic Pseudoureas”
Tetrahedron Letters 1976, 17, 1145–1148
S. Tsuboi, P. Stromquist and L. E. Overman
16. “Synthesis of Trichloroacetamido-1,3-dienes. Useful Aminobutadiene Equivalents for the Diels–Alder Reaction”
Journal of the American Chemical Society 1976, 98, 2352–2355
L. E. Overman and L. A. Clizbe
15. “A General Method for the Synthesis of Amines by the Rearrangement of Allylic Trichloroacetimidates. 1,3-Transposition of Alcohol and Amine Functions”
Journal of the American Chemical Society 1976, 98, 2901–2910
L. E. Overman
14. “Nucleophilic Cleavage of the Sulfur–Sulfur Bond by Phosphorus Nucleophiles. IV. Kinetic Study of the Reduction of Alkyl Disulfides with Triphenylphosphine and Water”
Journal of the American Chemical Society 1976, 98, 771–775
L. E. Overman and E. M. O’Connor
13. “Allylically Transposed Amines from Allylic Alcohols: 3,7-Dimethyl-1,6-Octadien-3-Amine”
Organic Syntheses 1978, 58, 4–11: Collective Volume VI, pp 507–511
L. A. Clizbe and L. E. Overman
12. “Nucleophilic Cleavage of the Sulfur–Sulfur Bond by Phosphorus Nucleophiles III. Kinetic Study of the Reduction of a Series of Ethyl Aryl Disulfides with Triphenylphosphine and Water”
Journal of Organic Chemistry 1975, 40, 2779–2781
L. E. Overman and S. T. Petty
11. “Synthesis of 1-Azaspiro[5.5]undec-7-en-2-one”
Tetrahedron Letters 1975, 16, 1149–1152
L. E. Overman
10. “Nucleophilic Cleavage of the Sulfur-Sulfur Bond by Phosphorous Nucleophiles. Kinetic Study of the Reduction of Aryl Disulfides with Triphenylphosphine and Water”
Journal of the American Chemical Society 1974, 96, 6081–6089
L. E. Overman, D. Matzinger, E. M. O’Connor and J. D. Overman
9. “Hemiacetal-Mediated Reactions. Directed Synthesis of Diols and Acetals”
Journal of Organic Chemistry 1974, 39, 1474–1481
L. E. Overman and C. B. Campbell
8. “Thermal- and Mercuric Ion-Catalyzed [3,3]-Sigmatropic Rearrangements of Allylic Trichloroacetimidates. The 1,3-Transposition of Alcohol and Amine Functions”
Journal of the American Chemical Society 1974, 96, 597–599
L. E. Overman
7. “The Reduction of Aryl Disulfides with Triphenylphosphine and Water”
Synthesis 1974, 59–60
L. E. Overman, J. Smoot and J. D. Overman
6. “Intramolecular Delivery of a Water Equivalent in the Oxymercuration Reaction. Conversion of an Allylic Alcohol Into a cis-Vicinal Diol”
Journal of the Chemical Society, Chemical Communications 1972, 1196–1198
L. E. Overman
5. “Dehydrogenase Enzyme Models. Approximation of an Alcohol and a Pyridinium Ring”
Journal of Organic Chemistry 1972, 37, 4214–4218
L. E. Overman
4. “Solvolytic Rearrangements Accompanied by Multiple Alkyl Shifts”
Journal of the American Chemical Society 1971, 93, 2247–2253
H. W. Whitlock, Jr. and L. E. Overman
3. “An ‘Artificial Enzyme’ Combining a Metal Catalytic Group and Hydrophobic Binding Cavity”
Journal of the American Chemical Society 1970, 91, 1075–1077
R. Breslow and L. E. Overman
2. “The Chemical Behavior of o-Bis(phenylethynyl)benzene Toward Some Electrophilic and Nucleophilic Reagents”
Journal of Organic Chemistry 1969, 34, 879–886
H. W. Whitlock, Jr., P. V. Sandvick, L. E. Overman and P. B. Reichardt
1. “Angular Methylation”
Journal of Organic Chemistry 1969, 34, 1962–1963
H. W. Whitlock, Jr. and L. E. Overman
Patents
1. “Synthesis of Indolizidines Related to the Cardiotonic Pumiliotoxin A Alkaloids”
U.S. Patent 4,675,325 (issued June 23, 1987)
L. E. Overman and F. Ito
2. “GABA Receptor Antagonists Selective for GABArho Receptors”
U. S. Patent 5627169 (issued May 6, 1997)
R. Miledi, L. E. Overman, Y. Murata and R. Woodward
3. "ETP Derivatives”
U.S. Patent 9,527,868 (issued December 27, 2016)
L. Overman, M. Baumann, S. Nam, D. Horne, R. Jove
4. “ETP Derivatives”
US Patent 9,856,273 (issued January 2, 2018)
L. E. Overman, M. Baumann, S. Nam, D. Horne, R. Jove, J. Xie, C. Kowolik
