University of California, Irvine
Note: After 50 years at UCI, the Overman Lab closed in August 2021
The ability to design and synthesize new molecules is a tool of enormous power that chemists bring to molecular level investigations in many areas of science. Research in the Overman group centers on the invention of new transformations and strategies in organic synthesis, and the total synthesis of complex organic molecules having promising biological properties. In our studies, natural products with unusual structures often play a role in pointing out limitations of current chemical synthesis art, thereby stimulating us to develop new organic synthesis methods.